Evidence map›Paper›PMID 40467684›Full record

ArticleScientific reports2025

3D-printed temperature and shear stress-controlled rocker platform for enhanced biofilm incubation.

Daniel P G Nilsson, Krister Wiklund, Dmitry Malyshev, Magnus Andersson

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniel P G NilssonDepartment of Physics, Umeå University, Linnaeus väg 24, 901 87, Umeå, Sweden.
Krister WiklundDepartment of Physics, Umeå University, Linnaeus väg 24, 901 87, Umeå, Sweden.
Dmitry MalyshevDepartment of Physics, Umeå University, Linnaeus väg 24, 901 87, Umeå, Sweden.
Magnus AnderssonDepartment of Physics, Umeå University, Linnaeus väg 24, 901 87, Umeå, Sweden. magnus.andersson@umu.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growing biofilms of thermophilic (heat-loving) and psychrotrophic (cold-tolerant) bacteria pose several challenges due to specific environmental requirements. Thermophilic bacteria typically grow between 45 and 80 [Formula: see text]C, while psychrotrophic bacteria thrive between 0 and 15 [Formula: see text]C. Maintaining the precise temperature and fluid conditions required for biofilm growth can be technically challenging. To overcome these challenges, we designed the Bio-Rocker, a temperature- and shear stress-controlled rocker platform for biofilm incubation. The platform supports temperatures between - 9 and 99 [Formula: see text]C, while its digital controller can adjust the rocking speed from 1 to 99[Formula: see text]/s and set rocking angles up to ±19[Formula: see text]. This ability, together with data from analytical models and multi-physics simulations, provides control over the shear stress distribution at the growth surfaces, peaking at 2.4 N/m[Formula: see text]. Finally, we evaluated the system's ability to grow bacteria at different temperatures, shear stress, and materials by looking at the coverage and thickness of the biofilm, as well as the total biomass. A step-by-step guide, 3D CAD files, and controller software is provided for easy replication of the Bio-Rocker, using mostly 3D-printed and off-the-shelf components. We conclude that the Bio-Rocker's performance is comparable to high-end commercial systems like the Enviro-Genie (Scientific Industries) yet costs less than $350 dollars to produce.

Indexed as

BiofilmsPrinting, Three-DimensionalStress, MechanicalBacteriaShear StrengthTemperature3D printingBiofilmBio-RockerCFD simulationDesign-build-testLaboratory rockersOpen-source

Identifiers

PMID40467684
PMCPMC12137683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.