ArticleScientific reports2025
Ammonia sets limit to life and alters physiology independently of pH in Halomonas meridiana.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Ammonia as a parameter shaping habitability on icy moons.FEMS microbes · 2026Review
- Spatiotemporal Impacts of Enceladus- and Earth-relevant Ammonia Gas On Cultivation of Extremophile Halomonas meridiana.Microbial ecology · 2025Article
- Growth, physiology, and metabolism ofFrontiers in microbiology · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
Abstract
The subsurface oceans of icy moons, expected to retain appreciable concentrations of ammonia, are of significant interest to astrobiology. On Earth, ammonia is released in large quantities, primarily through anthropogenic activities. Ammonia is toxic to many forms of life at high concentrations, and thus it is necessary to understand the habitability impact of ammonia on these environments. The survival limits and physiological response of aerobic bacteria in ammonia, and whether ammonia toxicity is distinct from toxicity by high pH, is poorly understood. Here, we investigate the survival thresholds, growth kinetics, and metabolomic response of Halomonas meridiana in ammonia-water solutions and pH-matched sodium hydroxide solutions. Using closed- and open-air systems to mimic environments with NH
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Registered trials
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