SynthesisScientific reports2025
Neural correlates of implicit emotion regulation in mood and anxiety disorders: an fMRI meta-analytic review.
Synthesis in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Article
- Depressive Symptoms Are Associated With Altered Development of Amygdala-Ventrolateral Prefrontal Connectivity During Implicit Emotion Regulation Across Adolescence.Biological psychiatry · 2026Article
- A study on the association between sleep quality and mental health of township healthcare workers from the perspective of social support.Frontiers in public health · 2026Article
- The neural basis of explicit and implicit emotion regulation: a coordinate-based meta-analysis.Oxford open neuroscience · 2026Review
- Moral emotions in mental health: regulation and mediation.Frontiers in psychology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maladaptive implicit emotion regulation has been highlighted as a transdiagnostic characteristic of mood and anxiety disorders. Whilst clinical diagnosis has relied on signs and symptoms, the integration of clinical neurosciences is becoming more important as a means of enhancing assessment, diagnosis, and treatment. Thus, activation likelihood estimation (ALE) meta-analysis was conducted for whole-brain foci comparing implicit emotion regulation in a large sample of patients with mood and anxiety disorders and healthy controls. Twenty-four clinical studies were identified based on established criteria (e.g., DSM-5). ALE meta-analysis reported convergence of hypoactivation in patients (n = 432) in the right medial frontal gyrus (BA9), spreading to the right anterior cingulate gyrus (BA32); and in the left middle temporal gyrus (BA21), spreading to the left superior temporal gyrus (BA22). Convergence of hyperactivation was reported in patients (n = 536) in the left medial frontal gyrus (BA9), spreading to the left superior frontal gyrus and the left middle frontal gyrus. Separate analysis of the mood disorders subgroup further highlighted convergence of hyperactivation in the insula and claustrum. The implications of the current findings are discussed within the context of the Research Domain Criteria (RDoC) framework of developing diagnostic systems that are more predictive of treatment outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.