Evidence map›Paper›PMID 40467508›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Extensive Visceral Calciphylaxis in a Patient with End-stage Renal Disease: A Postmortem Revelation.

Naho Ito, Yuta Imai, Shoko Tsujiko, Yoshiki Okumura, Masanori Shiohara, Masamichi Bamba

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Naho ItoDepartment of Cardiology, Saiseikai Shiga Hospital, Japan.
Yuta ImaiDepartment of Cardiology, Saiseikai Shiga Hospital, Japan.
Shoko TsujikoDepartment of Plastic and Reconstructive Surgery, Saiseikai Shiga Hospital, Japan.
Yoshiki OkumuraDepartment of Emergency and Critical Care Medicine, Saiseikai Shiga Hospital, Japan.
Masanori ShioharaDepartment of Diagnostic Pathology, Saiseikai Shiga Hospital, Japan.
Masamichi BambaDepartment of Diagnostic Pathology, Saiseikai Shiga Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calciphylaxis is a rare, life-threatening condition in end-stage renal disease, often presenting with skin ulcers and potentially involving the internal organs. A 62-year-old man undergoing hemodialysis developed non-healing leg ulcers that were initially treated for cellulitis. The diagnosis was confirmed through a biopsy after ulceration and necrosis progressed. Despite multidisciplinary treatment, the patient died because of sepsis and intestinal perforation. Autopsy revealed extensive visceral calciphylaxis, highlighting the under-recognized systemic nature of the disease. This case emphasizes the need for heightened awareness and an early diagnosis as well as the role of autopsies in understanding calciphylaxis, particularly its potential to involve visceral organs, which may be underrecognized.

Indexed as

CalciphylaxisKidney Failure, ChronicVisceraAutopsyFatal OutcomeHumansMaleMiddle AgedRenal Dialysiscalciphylaxishemodialysis patientpathological autopsyskin ulcervisceral lesion

Identifiers

PMID40467508
PMCPMC12804439

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.