Evidence map›Paper›PMID 40467505›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Transbronchial Mediastinal Cryobiopsy in Diagnosing Sarcoidosis: A Three-Case Report.

Chieri Yamada, Ryota Otoshi, Eri Hagiwara, Asami Moriuchi, Yoichi Tagami, Takashi Niwa, Tomohisa Baba, Tomoe Sawazumi, Tamiko Takemura, Takashi Ogura

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chieri YamadaDepartment of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Japan.
Ryota OtoshiDepartment of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Japan.
Eri HagiwaraDepartment of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Japan.
Asami MoriuchiDepartment of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Japan.
Yoichi TagamiDepartment of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Japan.
Takashi NiwaDepartment of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Japan.
Tomohisa BabaDepartment of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Japan.
Tomoe SawazumiDepartment of Pathology, Kanagawa Cardiovascular and Respiratory Center, Japan.
Tamiko TakemuraDepartment of Pathology, Kanagawa Cardiovascular and Respiratory Center, Japan.
Takashi OguraDepartment of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent reports suggest that a transbronchial mediastinal cryobiopsy (TMC) offers a better diagnostic performance for benign diseases than endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) because it can obtain larger specimens. We herein report the utility of TMC in three patients with sarcoidosis at our institution. EBUS-TBNA failed to diagnose sarcoidosis in all three patients, whereas TMC provided a definitive diagnosis. Although no significant differences in either the safety or procedural complexity were observed between TMC and EBUS-TBNA, the cost of TMC remains a considerable challenge. Further research is required to determine the strategies regarding optimal patient selection for sarcoidosis patients who need a diagnosis of TMC.

Indexed as

BronchoscopyCryosurgeryMediastinumSarcoidosisSarcoidosis, PulmonaryAdultAgedEndoscopic Ultrasound-Guided Fine Needle AspirationFemaleHumansMaleMiddle Agedendobronchial ultrasound-guided transbronchial needle aspirationsarcoidosistransbronchial mediastinal cryobiopsy

Identifiers

PMID40467505
PMCPMC12804457

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.