Evidence map›Paper›PMID 40467499›Full record

ArticleInternal medicine (Tokyo, Japan)2025

An Autopsy Case of a Desmoplastic Small Round Cell Tumor with a Rapid Fatal Outcome due to Diffuse Cystic Liver Metastases.

Yosuke Saito, Tomomi Sanomachi, Shuhei Suzuki, Takanobu Kabasawa, Hidenori Sato, Hirofumi Watanabe, Fumiyoshi Fujishima, Hiroya Otake, Yuta Horie

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yosuke SaitoDepartment of Gastroenterology, Yamagata City Hospital Saiseikan, Japan.
Tomomi SanomachiDepartment of Medical Oncology, National Cancer Center Hospital, Japan.
Shuhei SuzukiDepartment of Clinical Oncology, Yamagata Prefectural Shinjo Hospital, Japan.
Takanobu KabasawaDepartment of Pathology, Yamagata University Faculty of Medicine, Japan.
Hidenori SatoDepartment of Genomic Information, Yamagata University Faculty of Medicine, Japan.
Hirofumi WatanabeDepartment of Pathology, Tohoku University Hospital, Japan.
Fumiyoshi FujishimaDepartment of Pathology, Tohoku University Hospital, Japan.
Hiroya OtakeDepartment of Pathology, Yamagata City Hospital Saiseikan, Japan.
Yuta HorieDepartment of Surgery, Yamagata City Hospital Saiseikan, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive malignancy with a poor prognosis. We report an autopsy case of DSRCT in a 24-year-old male with a rapidly fatal outcome due to unusual diffuse cystic liver metastases. Despite an initial complete response to therapy, the patient developed extensive hepatic involvement leading to acute liver failure. Autopsy revealed widespread DSRCT with cystic degeneration in the liver metastases, which was confirmed by EWSR1 rearrangement. This case highlights the unpredictable nature of DSRCT and its potential for an atypical presentation, while emphasizing the need for improved therapeutic strategies.

Indexed as

CystsDesmoplastic Small Round Cell TumorLiver NeoplasmsAutopsyFatal OutcomeHumansMaleRNA-Binding Protein EWSYoung AdultEWSR1 protein, humanRNA-Binding Protein EWScystic liver metastasesdesmoplastic small round cell tumorEWSR1-WT1 fusionultra-rare cancer

Identifiers

PMID40467499
PMCPMC12740349

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.