Evidence map›Paper›PMID 40467468›Full record

ReviewEndocrine journal2025

Utility of gel filtration chromatography in evaluating successful resection of ectopic adrenocorticotropic hormone-producing tumor: a case report and literature review.

Mei Nakatsuji, Hironori Bando, Masaaki Yamamoto, Maki Kanzawa, Takefumi Doi, Yasutaka Tsujimoto, Kei Yoshino, Hidenori Fukuoka, Itsuko Sato, Yoshihiko Yano and 2 more

Abstract readCase ReportsReview
In one paragraph

Review in Endocrine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mei NakatsujiDivision of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Hospital, Kobe, Japan.
Hironori BandoDivision of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Hospital, Kobe, Japan.ORCID http://orcid.org/0000-0002-7421-2714
Masaaki YamamotoDivision of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Hospital, Kobe, Japan.ORCID http://orcid.org/0000-0002-7000-8134
Maki KanzawaDivision of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe, Japan.ORCID http://orcid.org/0000-0003-2806-2011
Takefumi DoiDivision of Thoracic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.ORCID http://orcid.org/0000-0003-1092-0700
Yasutaka TsujimotoDivision of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Hospital, Kobe, Japan.
Kei YoshinoDivision of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Hospital, Kobe, Japan.ORCID http://orcid.org/0000-0002-8062-4379
Hidenori FukuokaDivision of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Hospital, Kobe, Japan.ORCID http://orcid.org/0000-0001-9255-653X
Itsuko SatoDepartment of Clinical Laboratory, Kobe University Hospital, Kobe, Japan.
Yoshihiko YanoDepartment of Clinical Laboratory, Kobe University Hospital, Kobe, Japan.ORCID http://orcid.org/0000-0002-5177-7480
Yugo TanakaDivision of Thoracic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.ORCID http://orcid.org/0000-0002-6541-1754
Wataru OgawaDivision of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.ORCID http://orcid.org/0000-0002-0432-4366

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ectopic adrenocorticotropic hormone (ACTH) syndrome resulting from ectopically secreting tumors poses a significant clinical challenge. Accurately identifying the tumor source and achieving curative resection are pivotal for patient prognosis; however, achieving these objectives is often complicated by complex ACTH secretion patterns. High-molecular-weight ACTH, frequently secreted by ectopic ACTH-producing tumors, is distinct from the conventional 39-amino-acid ACTH (ACTH

Indexed as

ACTH Syndrome, EctopicAdrenocorticotropic HormoneChromatography, GelNeuroendocrine TumorsThymus NeoplasmsAdultHumansMaleTreatment OutcomeAdrenocorticotropic HormoneEctopic ACTH syndromeGel filtration chromatographyHigh-molecular-weight ACTH

Identifiers

PMID40467468
PMCPMC12510779

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.