Evidence map›Paper›PMID 40467343›Full record

ArticleBiomacromolecules2025

Physicochemical Reinforcement of Hydrophilic Gelatin Films by Fibroin Nanofibrils Prepared via Cellulose-Assisted Self-Assembly.

Yurim Kim, Juhee Yoon, Hyemin Kim, Sunyoung Yoon, Jimin Lim, Seon-Gyeong Kim, Hyoung-Joon Jin, Hyo Won Kwak

Abstract read
In one paragraph

Article in Biomacromolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yurim KimProgram in Environmental and Polymer Engineering, Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of Korea.
Juhee YoonProgram in Environmental and Polymer Engineering, Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of Korea.
Hyemin KimProgram in Environmental and Polymer Engineering, Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of Korea.
Sunyoung YoonProgram in Environmental and Polymer Engineering, Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of Korea.
Jimin LimProgram in Environmental and Polymer Engineering, Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of Korea.
Seon-Gyeong KimDepartment of Agriculture, Forestry and Bioresources, College of Agriculture & Life Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea.
Hyoung-Joon JinProgram in Environmental and Polymer Engineering, Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of Korea.ORCID 0000-0002-1763-9455
Hyo Won KwakDepartment of Agriculture, Forestry and Bioresources, College of Agriculture & Life Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea.ORCID 0000-0003-1630-7210

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study developed cellulose-assisted silk nanofibrils through a templated cellulose regeneration process. During cellulose dissolution and regeneration, the structure of silk fibroin transitioned into β-sheet, facilitating its self-assembly into nanofibrils. These cellulose-assisted fibroin nanofibrils exhibited excellent dispersion stability and optical properties. When incorporated as nanofillers in gelatin based composite films, these nanofibrils, unlike cellulose nanofibrils, directly participated in the fructose-mediated Maillard reaction. This led to enhanced structural densification and functionalization. The combination of the Maillard reaction and the cellulose-assisted fibroin nanofibrils had a synergistic effect, resulting in significant improvements in mechanical properties, including tensile strength (17.68 ± 0.39 MPa), Young's modulus (476.59 ± 1.39 MPa), and tensile strain (442.45% ± 4.93%). Moreover, the film exhibited strong ultraviolet-blocking capabilities, enhanced moisture barrier properties, and excellent antioxidant activity. As a result, the cross-linked cellulose-assisted fibroin nanofibril reinforced gelatin composite film demonstrated excellent performance as a food packaging material, effectively inhibiting bacterial growth and reducing weight loss. These findings suggest that silk-based nanofibrils capable of participating in chemical cross-linking can serve as robust physicochemical reinforcing agents and functional fillers for protein-based edible packaging films.

Indexed as

CelluloseFibroinsGelatinNanofibersAntioxidantsFood PackagingHydrophobic and Hydrophilic InteractionsTensile StrengthAntioxidantsCelluloseFibroinsGelatin

Identifiers

PMID40467343
PMCPMC12264942

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.