Evidence map›Paper›PMID 40467121›Full record

Trial reportJournal of the American Dental Association (1939)2025

Evaluating effects of animal-assisted therapy on pediatric dental care patients: A pilot clinical trial.

Jacqueline Massouda, Nare Ghaltakhchyan, Jennifer Judd, Clare Bocklage, Raven Selden, Olivia TumSuden, Eleanor Nanney, Jessica Lee, Jeannie Ginnis, Timothy Strauman and 5 more

2 registry-linked trialsAbstract readClinical Trial
In one paragraph

Trial report in Journal of the American Dental Association (1939), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04708028 nacompletednot on this map

Animal Assisted Therapy's Effects on Dental Patients

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2021 to 2024Enrolled40ConditionsAnxietyArmsDog Therapy
NCT07448714 nacompletednot on this map

Animal Assisted Therapy as a Behavioral Management Technique During Dental Treatment in Pediatric Patients

TypeinterventionalSponsorUniversity of Puerto RicoRan2023 to 2024Enrolled20ConditionsDental Fear and Anxiety, Animal Assisted Therapy, Dental TreatmentArmsanimal assisted therapy
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Dog-assisted therapy in paediatric dentistry: physiological, psychological, and family-centred benefits in managing child dental anxiety.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Jacqueline Massouda
Nare Ghaltakhchyan
Jennifer Judd
Clare Bocklage
Raven Selden
Olivia TumSuden
Eleanor Nanney
Jessica Lee
Jeannie Ginnis
Timothy Strauman
Caroline Sawicki
Eric A Hodges
Christina Graves
Kimon Divaris
Laura Jacox

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational and Clinical Sciences Institute (NC TraCS)UM1TR004406 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NICHOLAS J SHAHEEN · 2023 to 2026
$37.5M
Orthognathic speech pathology: Understanding how jaw disharmonies and their surgical correction influence speechK08DE030235 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JACOX, LAURA ANNE · 2021 to 2025
$889k
Evaluating the Effects of Animal Therapy on Anxiety in Pediatric Dental PatientsR03DE032768 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JACOX, LAURA ANNE · 2023 to 2024
$308k
NCATS NIH HHS UL1 TR002489NCATS NIH HHS UM1 TR004406NIDCR NIH HHS K08 DE030235NIDCR NIH HHS R03 DE032768
6 · The paper itself

Abstract

backgroundAn estimated 6% through 22% of children have dental anxiety, which can contribute to disruptive behavior and oral health care avoidance. Evidence from medical settings indicate reductions in pain and stress after therapy dog implementation. To identify a low-risk, nonpharmacologic approach for anxiety and pain management in dentistry, a pilot prospective clinical trial was conducted to determine best practices for evaluating the efficacy of animal-assisted therapy (AAT).

methodsThe effects of AAT on pediatric patients were measured through physiological, objective measures (ie, heart rate, salivary cortisol and α-amylase, and video coding) and validated self-reported scales of anxiety, fear, and pain, during an invasive dental procedure. Children aged 7 through 14 years were consecutively enrolled into an AAT (n = 18) or control (n = 21) group. Participants underwent an operative or surgical (eg, extraction) dental procedure. Descriptive and bivariate statistics were used.

resultsParticipants in the AAT group reported significantly less postoperative pain than those in the control group (P = .001). The heart rates of AAT participants dropped after key events and had less variation than control participants. Objective video coding revealed that AAT participants had significantly longer durations of relaxed lower bodies than control participants (P = .204). No differences were seen in salivary cortisol and α-amylase. These physiological and self-report measures are feasible for use in future studies.

conclusionsAAT may be an effective therapy for alleviating anxiety and pain in pediatric dental patients and warrants additional study using both objective physiological end points and subjective self-report measures. PRACTICAL IMPLICATIONS: Pending further research, canine therapy may be a valuable addition to dental clinics for anxiety and pain management. This clinical trial was registered at ClinicalTrials.gov. The registration number is NCT04708028.

Indexed as

Animal Assisted TherapyDental AnxietyDental Care for ChildrenAdolescentalpha-AmylasesAnimalsChildDogsFemaleHeart RateHumansHydrocortisoneMalePain ManagementPain MeasurementPilot Projectsalpha-AmylasesHydrocortisoneanimal therapyDental anxietypediatric dentistry

Identifiers

PMID40467121
PMCPMC12356166

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.