Evidence map›Paper›PMID 40467089›Full record

ArticleBMJ global health2025

Importance of outbreak response research in bridging knowledge gaps on emerging infectious diseases.

Robert F Breiman, Eric Osoro, Richard Reithinger, David Wang, Michael Diamond, Wesley C Van Voorhis, Judith N Wasserheit, Peter MacGarr Rabinowitz, Souleymane Mboup, Jennifer J Hemingway-Foday and 15 more

Abstract read
In one paragraph

Article in BMJ global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Robert F Breiman *Rollins School for Public Health, Emory University, Atlanta, Georgia, USA.
Eric OsoroCenter for Research in Emerging Infectious Diseases-East and Central Africa, Washington State University, Nairobi, Kenya.
Richard ReithingerCenter for Research in Emerging Infectious Diseases Network Coordinating Center, Research Triangle Institute, Research Triangle Park, North Carolina, USA.
David WangCenter for Research in Emerging Infectious Diseases-Epidemiology, Surveillance, Pathogenesis, Washington University in St Louis, St Louis, Missouri, USA.
Michael DiamondCenter for Research in Emerging Infectious Diseases-Epidemiology, Surveillance, Pathogenesis, Washington University in St Louis, St Louis, Missouri, USA.
Wesley C Van VoorhisUnited World Antiviral Research Network, University of Washington, Seattle, Washington, USA.ORCID http://orcid.org/0000-0001-6141-2015
Judith N WasserheitMedical School, University of Washington, Seattle, Washington, USA.
Peter MacGarr RabinowitzEnvironmental and Occupational Health Sciences, University of Washington Center for One Health, Seattle, Washington, USA.
Souleymane MboupInstitut de Recherche en Santé de Surveillance Epidémiologique et de Formations, Dakar, Senegal.
Jennifer J Hemingway-FodayRTI Int, Raleigh, North Carolina, USA.
Tulio de OliveiraStellenbosch University, Stellenbosch, South Africa.
Adrianus C M BoonCenter for Research in Emerging Infectious Diseases-Epidemiology, Surveillance, Pathogenesis, Washington University in St Louis, St Louis, Missouri, USA.
J S SchieffelinPediatrics, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Gregory D SempowskiCenter for Research in Emerging Infectious Diseases Network Coordinating Center, Research Triangle Institute, Research Triangle Park, North Carolina, USA.
M Anthony MoodyDuke University, Durham, North Carolina, USA.
Nikos VasilakisUniversity of Texas Medical Branch, Galveston, Texas, USA.
Kathryn A HanleyNew Mexico State University, Las Cruces, New Mexico, USA.
Carolyne NasimiyuPaul G. Allen School For Global Health, Washington State University, Pullman, Washington, USA.
Silvia SitumaPaul Allen School for Global Health, Washington State University Global Health Program-Kenya, Nairobi, Kenya.
Isaac NgereWashington State University, Pullman, Washington, USA.
Henry Kyobe BosaOutbreaks and Epidemics, Republic of Uganda Ministry of Health, Kampala, Uganda.ORCID http://orcid.org/0000-0001-6593-8727
Luke NyakarahukaEmerging and Re-emerging infectious diseases, Uganda Virus Research Institute, Entebbe, Uganda.
Barnabas BakamutumahoUganda Virus Research Institute, Entebbe, Uganda.
Sara E WoodsonNational Institutes of Health, Bethesda, Maryland, USA.
M Kariuki Njenga *Washington State University, Pullman, Washington, USA mkariuki.njenga@wsu.edu.ORCID http://orcid.org/0000-0002-7629-7002

Funding

Emerging Infectious Diseases Research Centers Coordination Center (EIDRC CC)U01AI151378 · NIAID · RESEARCH TRIANGLE INSTITUTE · PI Gregory D Sempowski · 2020 to 2026
$14.7M
University of Washington Arboviral Research Network (UWARN)U01AI151698 · NIAID · UNIVERSITY OF WASHINGTON · PI Michael Gale, PETER MACGARR RABINOWITZ · 2020 to 2026
$13.3M
West African Emerging Infectious Disease Research Center (WA-EIDRC)U01AI151812 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI ANDERSEN, KRISTIAN GRAUGAARD, GARRY, ROBERT F · 2020 to 2024
$13.2M
Emerging Infectious Diseases Research Center - East and Central AfricaU01AI151799 · NIAID · WASHINGTON STATE UNIVERSITY · PI M KARIUKI NJENGA · 2020 to 2026
$10.4M
West African Center for Emerging Infectious DiseasesU01AI151801 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Robert W Cross, Scott C Weaver · 2020 to 2026
$10.1M
Emerging infections: surveillance, epidemiology and pathogenesisU01AI151810 · NIAID · WASHINGTON UNIVERSITY · PI Adrianus CM Boon, DAVID WANG · 2020 to 2026
$10.0M
Coordinating Research on Emerging Arboviral Threats Encompassing the Neotropics II (CREATE-NEO II)U01AI151807 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Kathryn Alyce Hanley, MAURICIO Lacerda NOGUEIRA · 2020 to 2026
$9.8M
Zoonotic and Emerging Infectious Diseases Training ProgramD43TW011519 · FIC · WASHINGTON STATE UNIVERSITY · PI Walter Godfrey Jaoko, Thumbi Mwangi · 2020 to 2026
$1.2M
FIC NIH HHS D43 TW011519NIAID NIH HHS U01 AI151378NIAID NIH HHS U01 AI151698NIAID NIH HHS U01 AI151799NIAID NIH HHS U01 AI151801NIAID NIH HHS U01 AI151807NIAID NIH HHS U01 AI151810NIAID NIH HHS U01 AI151812
6 · The paper itself

Abstract

An important outcome of the devastating 2014 West African Ebola virus disease outbreak and the 2020 COVID-19 pandemic has been the growing promotion of conducting research during outbreaks of emerging infectious diseases (EIDs) as a valuable and acceptable process of acquiring knowledge to enhance our ability to better prevent and control these diseases in the future. Recognising the unique opportunity during outbreaks to leverage increases in cases over a short time interval and in a circumscribed area, we articulate a systematic process of conducting EID outbreak response research, highlighting knowledge gaps that should be prioritised, and measures that can be applied to mitigate numerous barriers commonly experienced during such times. We also highlight ethical considerations that must be addressed to minimise practices that continue to erode global confidence in sharing specimens and data.

Indexed as

Biomedical ResearchCommunicable Diseases, EmergingDisease OutbreaksCOVID-19Hemorrhagic Fever, EbolaHumansSARS-CoV-2EpidemiologyGlobal HealthInfections, diseases, disorders, injuriesPublic Health

Identifiers

PMID40467089
PMCPMC12142168

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.