Evidence map›Paper›PMID 40466050›Full record

ArticleCritical care explorations2025

Quantifying Healthcare Provider Perceptions of a Novel Deep Learning Algorithm to Predict Sepsis: Electronic Survey.

Karthik Ramesh, Aaron Boussina, Supreeth P Shashikumar, Atul Malhotra, Christopher A Longhurst, Christopher S Josef, Kimberly Quintero, Jake Del Rosso, Shamim Nemati, Gabriel Wardi

Abstract read
In one paragraph

Article in Critical care explorations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Karthik RameshSchool of Medicine, University of California San Diego, San Diego, CA.ORCID 0000-0003-2938-7942
Aaron BoussinaDepartment of Medicine, University of California San Diego, San Diego, CA.
Supreeth P ShashikumarDepartment of Medicine, University of California San Diego, San Diego, CA.
Atul MalhotraDepartment of Medicine, University of California San Diego, San Diego, CA.
Christopher A LonghurstDepartment of Medicine, University of California San Diego, San Diego, CA.
Christopher S JosefClairyon, La Jolla, CA.
Kimberly QuinteroDepartment of Quality, University of California San Diego, San Diego, CA.
Jake Del RossoDepartment of Emergency Medicine, Cottage Hospital, Santa Barbara, CA.
Shamim NematiDepartment of Medicine, University of California San Diego, San Diego, CA.
Gabriel WardiDepartment of Medicine, University of California San Diego, San Diego, CA.

Funding

San Diego Biomedical Informatics Education & Research (SABER)T15LM011271 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHAMIM NEMATI · 2012 to 2026
$9.7M
VentNet: A Real-Time Multimodal Data Integration Model for Prediction of Respiratory Failure in Patients with COVID-19R01HL157985 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, NEMATI, SHAMIM · 2022 to 2025
$2.9M
GeneRAlizable Sepsis Phenotyping (GRASP) using Electronic Health Records and Continuous Monitoring SensorsR35GM143121 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NEMATI, SHAMIM · 2021 to 2025
$2.2M
RAAB-AI: Reducing Automation and Anchoring Bias in AI SystemsR01LM013998 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHAMIM NEMATI · 2022 to 2026
$1.7M
AIVIS: Next Generation Vigilant Information Seeking Artificial Intelligence-based Clinical Decision Support for SepsisR42AI177108 · NIAID · HEALCISIO, INC. · PI JOSEF, CHRISTOPHER · 2023 to 2024
$1.3M
Implementation of Continuum of Care Sepsis Phenotyping and Risk StratificationK23GM146092 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Gabriel Wardi · 2022 to 2026
$898k
NHLBI NIH HHS R01 HL157985NIAID NIH HHS R42 AI177108NIGMS NIH HHS K23 GM146092NIGMS NIH HHS R35 GM143121NLM NIH HHS R01 LM013998NLM NIH HHS T15 LM011271U.S National Institutes of Health R01LM013998, R01HL157985, R35GM143121
6 · The paper itself

Abstract

importanceSepsis is a major cause of morbidity and mortality, with early intervention shown to improve outcomes. Predictive modeling and artificial intelligence (AI) can aid in early sepsis recognition, but there remains a gap between algorithm development and clinical use. Despite the importance of user experience in adopting clinical predictive models, few studies have focused on provider acceptance and feedback.

objectivesTo evaluate healthcare worker perception and acceptance of a deep learning sepsis prediction model in the emergency department (ED). DESIGN, SETTING, AND

participantsCOnformal Multidimensional Prediction Of SEpsis Risk (COMPOSER), a deep learning algorithm, is used at two EDs of a large academic medical center to predict sepsis before clear clinical presentation. An internally developed survey following the Checklist for Reporting Results of Internet E-Surveys was distributed to team members who received a COMPOSER alert. ANALYSIS: Mann-Whitney U testing was performed on results stratified by provider experience.

resultsA total of 114 responses were received: 76 from doctors of medicine/doctors of osteopathic medicine, 34 from registered nurses, and four from nurse practicioners/physician assistants. Of these, 53% were from providers with fewer than 5 years of experience. Seventy-seven percent of respondents had a positive or neutral perception of the alert's usefulness. Providers with 0-5 years of experience were more likely to expect sepsis after the alert (p = 0.021) and found the alert more useful (p = 0.016) compared with those with 6+ years of experience. Additionally, physicians with 0-5 years of experience were more likely to say the alert changed their patient management (p = 0.048).

conclusionsLess experienced providers were more likely to perceive benefit from the alert, which was overall received favorably. Future AI implementations might consider tailored alert patterns and education to enhance reception and reduce fatigue.

Indexed as

AlgorithmsAttitude of Health PersonnelDeep LearningHealth PersonnelSepsisAcademic Medical CentersEmergency Service, HospitalHumansSurveys and Questionnairesdeep learningimplementationperceptionssepsissurvey

Identifiers

PMID40466050
PMCPMC12140755

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.