Evidence map›Paper›PMID 40466034›Full record

ArticleJCO oncology practice2026

Fertility Preservation Services for Adolescents and Young Adults: 2022 National Cancer Institute Community Oncology Research Program Landscape Assessment.

Erin M Mobley, Julie Anna Wolfson, Jennifer Levine, Lingyun Ji, Subhash Ramakrishnan, Chandylen L Nightingale, Emily V Dressler, Carol Kittel, David R Freyer, Aaron J Sugalski and 8 more

Abstract read
In one paragraph

Article in JCO oncology practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Initial development and usability testing of a digital fertility preservation navigator for newly diagnosed young adult cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Erin M MobleyDepartment of Surgery, College of Medicine Jacksonville, University of Florida, Jacksonville, FL.ORCID 0000-0002-6278-6593
Julie Anna WolfsonDivision of Pediatric Hematology-Oncology, University of Alabama at Birmingham, Birmingham, AL.ORCID 0000-0002-3711-2239
Jennifer LevineCenter for Cancer and Blood Disorders, Children's National Medical Center, Washington, DC.ORCID 0000-0003-1417-0169
Lingyun JiDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA.ORCID 0000-0003-2500-1993
Subhash RamakrishnanChildren's Oncology Group, Los Angeles, CA.ORCID 0009-0006-5801-8985
Chandylen L NightingaleDepartment of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC.ORCID 0000-0002-2275-9849
Emily V DresslerDepartment of Biostatistics and Data Science, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC.ORCID 0000-0002-6054-7839
Carol KittelDepartment of Biostatistics and Data Science, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC.ORCID 0000-0002-4512-0634
David R FreyerChildren's Hospital Los Angeles and USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA.ORCID 0000-0001-5280-990X
Aaron J SugalskiUniversity of Texas Health Science Center San Antonio, San Antonio, TX.ORCID 0009-0007-6945-6179
Pinki Kumari PrasadDivision of Hematology/Oncology, Department of Pediatrics, Louisiana State University Health, New Orleans, LA.
Jessica Sheth BhutadaChildren's Hospital Los Angeles and USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Karly MurphyDepartment of Psychology, Eastern Carolina University, Greenville, NC.ORCID 0000-0001-9174-1338
Wade KyonoDepartment of Pediatrics, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI.
Michael E RothDepartment of Pediatrics, University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-6411-8353
Susan K ParsonsDepartments of Medicine and Pediatrics, Tufts University School of Medicine, and Division of Hematology/Oncology, Tufts Medical Center, Boston, MA.ORCID 0000-0003-0282-6490
Melissa P BeaucheminSchool of Nursing, Columbia University Irving Medical Center, New York, NY.ORCID 0000-0003-4058-1586
Landscape Committee

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
Towards a preventive cancer vaccine for children with constitutional mismatch repair deficiencyUG1CA189955 · NCI · PUBLIC HEALTH INSTITUTE · PI BRAD H POLLOCK, Michael E. Roth · 2014 to 2026
$62.5M
Wake Forest NCORP Research BaseUG1CA189824 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Emily Van Meter Dressler, GLENN J LESSER · 2014 to 2026
$57.9M
iManageAYA: Preparation and Optimization of a mHealth Intervention for Managing Depressive Symptoms in Adolescent and Young adult Cancer SurvivorsR00CA248701 · NCI · EAST CAROLINA UNIVERSITY · PI MURPHY, KARLY MARY · 2023 to 2025
$630k
NCI NIH HHS R00 CA248701NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899NCI NIH HHS UG1 CA189824NCI NIH HHS UG1 CA189955
6 · The paper itself

Abstract

purposeGiven the impact of cancer treatment on fertility among adolescents and young adults (AYAs: 15-39 years), it is important to ensure AYAs access to fertility preservation (FP). However, the availability of FP services for AYAs treated in community settings is unknown. We examined FP access at National Cancer Institute Community Oncology Research Program (NCORP) practice groups.

methodsThe 2022 NCORP Landscape Assessment survey captured available resources and cancer care services including FP services at practice groups. We described FP services as accessible (on-site or off-site) versus not accessible by AYA-treating status (as previously defined). Univariable and multivariable analyses were used to evaluate associations between FP services and practice characteristics (NCORP classification [minority/underserved or community] and proportion of Medicaid or uninsured above/below the national average).

resultsAmong 271 practice groups responding to the survey, 100 were categorized as AYA-treating, of which 32% had neither male nor female FP services available. Sperm banking was available at 59 AYA-treating practices, among which 43 (73%) referred for sperm banking off-site. Although approximately half of AYA-treating practices reported accessible female FP services (embryo = 54%, oocyte = 55%, ovarian tissue = 40%), most of them referred patients off-site (embryo = 72%, oocyte = 80%, ovarian tissue = 83%). The odds of access to male FP were lower at minority/underserved practices (odds ratio, 0.34 [95% CI, 0.13 to 0.88];

conclusionDespite guidelines surrounding FP discussions before cancer therapy, and strong consensus regarding the importance of FP access, many AYA-treating practices in community settings lack access to FP services. Understanding how to leverage available services and broadly expand access is urgently needed to facilitate guideline-concordant, high-quality cancer care for AYAs.

Indexed as

Fertility PreservationNeoplasmsAdolescentAdultFemaleHealth Services AccessibilityHumansMaleNational Cancer Institute (U.S.)United StatesYoung Adult

Identifiers

PMID40466034
PMCPMC12353215

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.