Trial reportRevista da Associacao Medica Brasileira (1992)2025
The effect of auricular vagus nerve stimulation in women with temporomandibular joint disorders: a randomized controlled study.
Trial report in Revista da Associacao Medica Brasileira (1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05500716 (The Effect of Application of Vagus Nerve Stimulation on the Treatment Efficiency in Temporomandibular Joint Dysfunction Caused by Myofascial Pain Syndrome), which is not on this map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Application of Vagus Nerve Stimulation on the Treatment Efficiency in Temporomandibular Joint Dysfunction Caused by Myofascial Pain Syndrome
Who cites it
1 citing paper in PubMed.
- Diagnosis-based pathways for conservative and minimally invasive management of temporomandibular disorders: a scoping review.Journal of oral & facial pain and headache · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTemporomandibular disorders associated with myofascial pain syndrome cause pain and disability in daily life. The aim of this study was to investigate the effect of auricular vagus nerve stimulation on pain in women with myofascial pain syndrome-related temporomandibular disorder.
methodsA total of 50 women with myofascial pain syndrome-related temporomandibular disorder aged between 18 and 35 years participated in this study. The vagus group (n=25) received auricular vagus nerve stimulation and manual therapy and exercise, and the control group (n=25) received only manual therapy and exercise twice a week for 3 months. The pressure pain threshold was used for the assessment.
resultsIn the vagus group, pressure pain threshold on the masseter, temporalis, sternocleidomastoid, digastricus, trapezius, and levator scapula muscles increased statistically significantly after treatment compared to baseline (p<0.05). In the control group, pressure pain threshold on the masseter and levator scapula muscles increased (p<0.05), while no statistically significant difference was found in the pressure pain threshold on the temporalis, sternocleidomastoid, digastricus, and trapezius muscles (p>0.05). When both groups were compared, vagus group was found to be more effective than control group in increasing pressure pain threshold in the masseter, trapezius, and levator scapula muscles (p<0.05).
conclusionAuricular vagus nerve stimulation was found to be effective in increasing pressure pain threshold in patients with myofascial pain syndrome-related temporomandibular disorder. The clinical trial registration number was NCT05500716.
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Registered trials
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