Evidence map›Paper›PMID 40465966›Full record

ReviewDental press journal of orthodontics2025

Developmental enamel defects: a must-know for orthodontic practice.

Marco Aurélio Benini Paschoal, Gabriele Andrade-Maia, Letícia Cristine-Silva, Aniely Ferreira Nogueira, Felícia Miranda, Daniela Garib

Abstract readReview
In one paragraph

Review in Dental press journal of orthodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marco Aurélio Benini PaschoalFederal University of Minas Gerais, Dental School, Department of Pediatric Dentistry (Belo Horizonte/MG, Brazil).ORCID http://orcid.org/0000-0002-3396-4688
Gabriele Andrade-MaiaFederal University of Minas Gerais, Dental School, post-graduate Program in Dentistry (Belo Horizonte/MG, Brazil).ORCID http://orcid.org/0000-0002-1604-3449
Letícia Cristine-SilvaFederal University of Minas Gerais, Dental School, post-graduate Program in Dentistry (Belo Horizonte/MG, Brazil).ORCID http://orcid.org/0000-0001-9397-5007
Aniely Ferreira NogueiraFederal University of Minas Gerais, Dental School, post-graduate Program in Dentistry (Belo Horizonte/MG, Brazil).ORCID http://orcid.org/0009-0007-0298-6255
Felícia MirandaUniversity of São Paulo, Dental School, Department of Orthodontics (Bauru/SP, Brazil).ORCID http://orcid.org/0000-0002-4015-0623
Daniela GaribUniversity of São Paulo, Dental School, Department of Orthodontics (Bauru/SP, Brazil).ORCID http://orcid.org/0000-0002-2449-1620

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDevelopmental Enamel Defects (DED) pose a significant challenge for clinicians, particularly orthodontists. These defects can lead to difficulties in differential diagnosis, orthodontic appliance adhesion, treatment planning, and overall patient management.

objectiveThe present review aims to provide orthodontists with a comprehensive understanding of DED and their implications for orthodontic treatment. A systematic literature search was conducted to identify relevant studies on DED and their orthodontic management.

resultsThe available evidence, primarily from laboratory-based studies, is of low to moderate quality. The most challenging DED cases involve structural loss, especially in molars severely affected by molar-incisor hypomineralization (MIH) and certain types of amelogenesis imperfecta.

conclusionsTo address the limitations of current research, well-designed clinical studies are needed to investigate various aspects of DED management, including pre-treatment of affected enamel, adhesive techniques for bracket bonding and removal, extraction of molars affected by MIH, and interdisciplinary collaboration among dental specialists. By advancing the understanding of DED and refining treatment strategies, orthodontists can improve the outcomes for patients with these conditions.

Indexed as

Dental EnamelDental Enamel HypoplasiaOrthodontics, CorrectiveAmelogenesis ImperfectaDental BondingHumansOrthodontic BracketsOrthodontics

Identifiers

PMID40465966
PMCPMC12133151

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.