ArticleScience advances2025
Precision-controlled sequential drug release via electrochemical corrosion of liquid metal nanoparticles.
Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Ga(III) ion release from gallium-based liquid metals: The trade-off between efficacy and safety.iScience · 2026Review
- Convergent methodologies in prosthetic joint infection research: integrating transdisciplinary approaches to understand and prevent biofilm-driven failure of orthopaedic prostheses.Journal of medical microbiology · 2026Review
- Harnessing spatiotemporal melatonin delivery from engineered platforms for targeted microenvironment remodeling in peripheral neuropathy.Materials today. Bio · 2026Review
- An implantable dual-chamber capsule with three release modes for site-specific delivery and enhanced therapeutic efficacy.iScience · 2026Article
- Gallium-Based Liquid Metals: From Properties to Applications.Nanomaterials (Basel, Switzerland) · 2026Review
- Nanofluidic-based electrochemical pump for remotely controlled, on-demand drug delivery.Lab on a chip · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An electrically controlled, programmable drug delivery system offers substantial potential in personalized biomedical devices. Current methods lack precise control over drug amounts and sequences, which is crucial for optimizing therapy. We present a solution with drug molecules modified onto gallium-based liquid metal nanoparticles (LMNPs) and using the electrochemical corrosion of LMNPs to controllably release the drugs, which allows arbitrary choice of drug types, release speed (fastest at less than 1 second), and sequence of release for customized therapy. This system applies to many types of drugs (molecules containing amine, thiol, hydroxyl, and carboxyl groups) and is integrated onto a stretchable thin film and can be implemented as epidermal or implantable devices. We tested the platform with antibiotics for wound infections and an antitumor drug for subcutaneous melanoma, confirming its excellent therapeutic efficacy and biocompatibility in both in vivo and in vitro tests.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.