ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2025
The Patient-reported Longitudinal Assessment Tool for OSA (PLATO): development and validation of a new clinical tool to assess response to obstructive sleep apnea treatment in adults.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07789834 (Application of the PLATO Questionnaire in Oral Appliance Therapy for Obstructive Sleep Apnea), which is not on this map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Application of the PLATO Questionnaire in Oral Appliance Therapy for Obstructive Sleep Apnea
Who cites it
2 citing papers in PubMed.
- Article
- Sleep apnea, how do we help thee? Let us count the ways.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesTo develop and validate a publicly available, patient-reported outcome (PRO) tool specific to obstructive sleep apnea (OSA) in adults, designed for clinical use to monitor treatment response and longitudinal symptom progression.
methodsThe PRO tool was developed in accordance with Food and Drug Administration guidance for PRO measures, utilizing a multiphase, mixed-methods approach. Part 1 involved concept elicitation and cognitive interviews with patients to identify key symptoms and impacts. Part 2 consisted of pilot testing the draft tool in 10 American Academy of Sleep Medicine-accredited sleep centers. Part 3 included psychometric validation using longitudinal online surveys in 560 adults with OSA and 40 controls. Analyses included exploratory factor analysis, Rasch modeling, test-retest reliability, internal consistency, construct validity, responsiveness to change, and determination of clinically important difference thresholds.
resultsThe final 11-item Patient-reported Longitudinal Assessment Tool for OSA has a 7-day recall period and assesses both daytime and nighttime OSA symptoms. It demonstrated strong internal consistency (α = 0.94), test-retest reliability (intraclass correlation coefficients = 0.91-0.97), and construct validity through moderate to strong correlations with established measures. The 11-item Patient-reported Longitudinal Assessment Tool for OSA scores discriminated between OSA severity and body mass index groups and were responsive to symptom improvement. The mean completion time was under 4 minutes. The tool can be used in both paper and electronic formats and has been translated into Spanish.
conclusionsThe 11-item Patient-reported Longitudinal Assessment Tool for OSA is a valid, reliable, and feasible PRO instrument for assessing OSA-related symptoms in clinical practice. It enables efficient monitoring of PROs across treatment stages. CITATION: Kirsch D, Abbasi-Feinberg F, Davies C, et al. The Patient-reported Longitudinal Assessment Tool for OSA (PLATO): development and validation of a new clinical tool to assess response to obstructive sleep apnea treatment in adults.
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Registered trials
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