Evidence map›Paper›PMID 40465395›Full record

ArticleKidney3602025

Nfkb1 Removal from Proximal Tubule Cells Improves Renal Tubular Outcomes Following Ischemia Reperfusion Injury.

Shun-Yang Cheng, Kari Koppitch, Jinjin Guo, Nathan Moy, Taylor L Simonian, Parker C Wilson, Andrew P McMahon

Abstract read
In one paragraph

Article in Kidney360, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shun-Yang ChengDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Kari KoppitchDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, Los Angeles, California.ORCID 0009-0007-3314-5651
Jinjin GuoDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Nathan MoyDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, Los Angeles, California.ORCID 0009-0005-4290-1661
Taylor L SimonianDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, Los Angeles, California.ORCID 0009-0004-7276-6918
Parker C WilsonDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0001-8647-9662
Andrew P McMahonDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine of the University of Southern California, Los Angeles, California.ORCID 0000-0002-3779-1729

Funding

VIRAL VECTOR COREP30DK019525 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI MITCHELL A. LAZAR · 1986 to 2026
$48.3M
Single-cell analysis to promote kidney repairUC2DK126024 · NIDDK · WASHINGTON UNIVERSITY · PI HUMPHREYS, BENJAMIN D., KIM, JUNHYONG · 2020 to 2024
$3.7M
Sexual dimorphism in the mammalian kidneyR01DK126925 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCMAHON, ANDREW P. · 2020 to 2024
$2.6M
The Single Cell Landscape of Early Human Diabetic NephropathyK08DK126847 · NIDDK · WASHINGTON UNIVERSITY · PI Parker C. Wilson · 2022 to 2026
$840k
Division of Diabetes, Endocrinology, and Metabolic Diseases R01DK126925NIDDK NIH HHS K08 DK126847NIDDK NIH HHS P30 DK019525NIDDK NIH HHS R01 DK126925NIDDK NIH HHS UC2 DK126024NIDDK NIH HHS UC2DK126024
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AKICKDischemia-reperfusion

Identifiers

PMID40465395
PMCPMC12407146

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.