Evidence map›Paper›PMID 40465291›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2025

Dynamic Liposome Sensing Platform to Wirelessly Ensure Nucleic Acid Encapsulation via Non-Contact Perception.

Younsu Jung, Jinhwa Park, Seonghun Shin, Sunghee Kim, Bijendra Bishow Maskey, Kiran Shrestha, Jianfu Ding, Thi Thuy Vy Tran, Patrick R L Malenfant, Jinkee Lee and 2 more

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Younsu JungDepartment of Biophysics, Institute of Quantum Biophysics, Research Engineering Center for R2R Printed Flexible Computer, Sungkyunkwan University, Suwon-si, 16419, Rep. of Korea.
Jinhwa ParkDepartment of Biophysics, Institute of Quantum Biophysics, Research Engineering Center for R2R Printed Flexible Computer, Sungkyunkwan University, Suwon-si, 16419, Rep. of Korea.
Seonghun ShinDepartment of Mechanical Engineering, Sungkyunkwan University, Suwon-si, 16419, Rep. of Korea.
Sunghee KimDepartment of Molecular Cell Biology, Sungkyunkwan University, Suwon-si, 16419, Rep. of Korea.
Bijendra Bishow MaskeyDepartment of Biophysics, Institute of Quantum Biophysics, Research Engineering Center for R2R Printed Flexible Computer, Sungkyunkwan University, Suwon-si, 16419, Rep. of Korea.
Kiran ShresthaDepartment of Biophysics, Institute of Quantum Biophysics, Research Engineering Center for R2R Printed Flexible Computer, Sungkyunkwan University, Suwon-si, 16419, Rep. of Korea.
Jianfu DingNational Research Council, RC, Ottawa, Ontario, K1A 0R6, Canada.
Thi Thuy Vy TranDepartment of Molecular Cell Biology, Sungkyunkwan University, Suwon-si, 16419, Rep. of Korea.
Patrick R L MalenfantNational Research Council, RC, Ottawa, Ontario, K1A 0R6, Canada.
Jinkee LeeDepartment of Mechanical Engineering, Sungkyunkwan University, Suwon-si, 16419, Rep. of Korea.ORCID 0000-0001-5590-0549
Jong-Sun KangDepartment of Molecular Cell Biology, Sungkyunkwan University, Suwon-si, 16419, Rep. of Korea.ORCID 0000-0001-9072-8211
Gyoujin ChoDepartment of Biophysics, Institute of Quantum Biophysics, Research Engineering Center for R2R Printed Flexible Computer, Sungkyunkwan University, Suwon-si, 16419, Rep. of Korea.ORCID 0000-0002-2451-5426

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The demand for a high-throughput and noncontact monitoring system to guarantee the payload of nucleic acid in liposomes is rapidly increasing for raising efficiency in gene therapeutics. Herein, inspired by electroreceptors of elasmobranch fishes, a dynamic liposome sensing (DLs) platform is developed by implementing the electret layer (CYTOP)-coated single-walled carbon nanotube-based thin film transistor (eSWCNT-TFT) which can monitor differences of the net-charge on deoxyribonucleic acid (DNA)-loaded liposomes. The SWCNT-TFTs are roll-to-roll (R2R) printed on plastic film and then, simply laminated by the droplet microfluidic chip to optimize the aqueous droplet lengths by controlling a ratio of injecting speed between oil to aqueous solution. The buffer solution, DNA-free liposomes, and DNA-loaded liposomes respectively induced different electrostatic potentials on eSWCNT-TFTs without direct contact with the electret layer, thereby shifting the threshold voltage (V

Indexed as

LiposomesNucleic AcidsWireless TechnologyDNANanotubes, CarbonDNALiposomesNanotubes, CarbonNucleic Acidsdroplet microfluidicslabel‐freeliposomeroll‐to‐rollthin‐film transistor

Identifiers

PMID40465291
PMCPMC12530037

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.