Evidence map›Paper›PMID 40465132›Full record

ArticleEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2025

Hypersensitivity associated with molar-incisor hypomineralisation (MIH) among elementary schoolchildren in Bavaria, Germany: results from a cross-sectional study.

R Gaballah, S Amend, K-F Fresen, H Schill, R Michel, V Pitchika, J Kühnisch, N Krämer

Abstract read
In one paragraph

Article in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Non- and minimally invasive management of hypersensitivity in molar-incisor hypomineralisation (MIH) at home and in clinical practice: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

R GaballahUniversity Medical Centre Giessen and Marburg (Campus Giessen), Medical Centre for Dentistry, Department of Paediatric Dentistry, Justus-Liebig-University Giessen, Giessen, Germany. Ramy.I.Gaballah@dentist.med.uni-giessen.de.
S AmendUniversity Medical Centre Giessen and Marburg (Campus Giessen), Medical Centre for Dentistry, Department of Paediatric Dentistry, Justus-Liebig-University Giessen, Giessen, Germany. Stefanie.Amend@dentist.med.uni-giessen.de.
K-F FresenUniversity Hospital, Department of Conservative Dentistry and Periodontology, Ludwig-Maximilians-University Munich, Munich, Germany.
H SchillUniversity Hospital, Department of Conservative Dentistry and Periodontology, Ludwig-Maximilians-University Munich, Munich, Germany.
R MichelCustomer Analytics, Deutsche Bank, Frankfurt am Main, Germany.
V PitchikaUniversity Hospital, Department of Conservative Dentistry and Periodontology, Ludwig-Maximilians-University Munich, Munich, Germany.
J KühnischUniversity Hospital, Department of Conservative Dentistry and Periodontology, Ludwig-Maximilians-University Munich, Munich, Germany.
N KrämerUniversity Medical Centre Giessen and Marburg (Campus Giessen), Medical Centre for Dentistry, Department of Paediatric Dentistry, Justus-Liebig-University Giessen, Giessen, Germany.

Funding

Bavarian State Ministry of Health, Care and Prevention through their health promotion program "Healthy Bavaria" (Gesund.Leben.Bayern.) 1225/2022
6 · The paper itself

Abstract

purposeThis cross-sectional epidemiological study aimed to provide population-based data on hypersensitivity associated with molar-incisor hypomineralisation (MIH) in 8- to 10-year-olds from Bavaria, Germany. It was hypothesized that hypersensitivity would be equally distributed among MIH teeth.

methodsA total of 5418 schoolchildren (8-10 years) were examined using the MIH criteria of the European Academy of Paediatric Dentistry (EAPD) and the MIH Treatment Need Index (MIH-TNI). MIH-TNI 1 was linked with mild MIH; MIH-TNI 2-4 corresponded to severe MIH. Hypersensitivity was recorded dichotomously (yes/no) after a two-second, 2.8-bar air blast (Schiff test). Descriptive statistics and a mixed-effects logistic regression model-adjusted for age, sex, region, tooth type, and caries status-explored hypersensitivity in MIH-affected teeth.

resultsThe MIH prevalence was 17.5% (n = 945). In this group, 9.8% of the children showed hypersensitivity in at least one tooth; 5.6% of all MIH-affected teeth were hypersensitive. Nearly half of the MIH-affected children (49.7%) presented severe MIH-TNI findings; MIH-TNI 2 was the most frequent finding (39.9%). Regression analyses indicated that demarcated opacities were significantly less likely to be associated with hypersensitivity (aOR = 0.054, p < 0.001). However, enamel breakdown did not show a significant association with hypersensitivity (aOR = 0.853, p = 0.693).

conclusionAlthough MIH was relatively common, overall hypersensitivity rates were low. Demarcated opacities were significantly less prone to hypersensitivity, yet enamel breakdown did not significantly differ from healthy teeth. Further standardised epidemiological research is needed to clarify variations in hypersensitivity rates and explore additional risk factors, e.g., breakdown depth or defect extension.

Indexed as

Dental Enamel HypoplasiaDentin SensitivityChildCross-Sectional StudiesFemaleGermanyHumansMaleMolarPrevalenceDental enamel hypomineralizationEpidemiologyHypersensitivityMolar hypomineralizationPost-eruptive breakdown

Identifiers

PMID40465132
PMCPMC12532631

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.