Evidence map›Paper›PMID 40465037›Full record

ReviewInflammopharmacology2025

A comprehensive review on anti-inflammatory plants: a mechanistic insight through preclinical and clinical studies.

Deepti Chaudhary, Saraswati Patel, Ritika Gururani, Pooja Chak, Sonika Jain, Jaya Dwivedi, Swapnil Sharma

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Biomolecules · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Deepti ChaudharyDepartment of Chemistry, Banasthali Vidyapith, Banasthali, Rajasthan, 304022, India.
Saraswati PatelSaveetha College of Pharmacy, Thandalam, Chennai, Tamil Nadu, India.
Ritika GururaniDepartment of Pharmacy, Banasthali Vidyapith, Banasthali, Rajasthan, 304022, India.
Pooja ChakDepartment of Chemistry, Banasthali Vidyapith, Banasthali, Rajasthan, 304022, India.
Sonika JainDepartment of Chemistry, Banasthali Vidyapith, Banasthali, Rajasthan, 304022, India.
Jaya DwivediDepartment of Chemistry, Banasthali Vidyapith, Banasthali, Rajasthan, 304022, India. jayadwivedi@yahoo.co.in.ORCID http://orcid.org/0000-0002-1524-7714
Swapnil SharmaDepartment of Pharmacy, Banasthali Vidyapith, Banasthali, Rajasthan, 304022, India. skspharmacology@gmail.com.ORCID http://orcid.org/0000-0003-2639-7096

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory diseases are a leading cause of morbidity and mortality worldwide, necessitating the exploration of novel therapeutic agents. Natural products, particularly plant-derived compounds, have emerged as promising candidates for managing inflammation due to their diverse bioactive constituents and significant safety. The present review provides a comprehensive analysis of the anti-inflammatory potential of medicinal plants, their mechanisms of action, and their therapeutic relevance in preclinical and clinical studies. A total of 94 medicinal plants and isolated compounds with reported anti-inflammatory activities have been discussed, with their mode of action including different signaling pathways, viz., inhibition of COX, LOX, cytokine modulation, and oxidative stress reduction. Despite substantial preclinical validation, the translation of these findings into clinical applications remains limited. Further research focusing on bioactive compound isolation, molecular pharmacology, and clinical trials is essential to establish plant-based therapeutics as viable alternatives to conventional anti-inflammatory drugs.

Indexed as

Anti-Inflammatory AgentsInflammationPlant ExtractsPlants, MedicinalAnimalsDrug Evaluation, PreclinicalHumansOxidative StressPhytotherapyAnti-Inflammatory AgentsPlant ExtractsArachidonic acid pathwayCytokinesInflammationMedicinal plantsPreclinical

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.