ReviewCardiovascular toxicology2025
Targeting Cardiotoxicity Induced by Environmental Toxins: The Role of Natural Products.
Review in Cardiovascular toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Environmental toxins such as heavy metals, industrial pollutants, pesticides, and environmental chemicals are becoming recognized as key contributors to cardiotoxicity, with considerable implications for worldwide cardiovascular health. Humans are unintentionally exposed to environmental toxins, which have a variety of cardiopathologic effects. These poisons cause oxidative stress, inflammation, mitochondrial dysfunction, and dysregulation of important physiological pathways which ultimately contribute to cardiac dysfunction and diseases. Natural compounds originating from medicinal plants, microbes, and marine organisms have emerged as promising cardioprotective agents. These bioactive chemicals exhibit potent anti-oxidant, anti-inflammatory, and cardio-regenerative activities, which target molecular mechanisms involved in cardiotoxicity. Phytochemicals such as terpenoids, polyphenols, flavonoids, and alkaloids, as well as bioactive peptides and microbial metabolites, have shown promise in pre-clinical and clinical investigations for preventing toxin-induced cardiac damage. Therefore, this review highlights the mechanisms of environmental toxin-induced cardiotoxicity and the novel therapeutic agents for the prevention and treatment of environmental toxin-induced cardiotoxicity.
Indexed as
Identifiers
40465026What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.