ArticleMolecular biotechnology2026
Biosynthesis of Silver Nanoparticles Using Endophytic Clonostachys rosea ZMS27 from Medicinal Plant Anemarrhena asphodeloides and its Antagonistic Activity Against Superficial Pathogenic Fungi.
Article in Molecular biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Superficial fungal infections (SFIs) represent a serious threat to global public health. It is known that silver nanoparticles (AgNPs) are characterized by potent antimicrobial properties. However, the therapeutic potential of biosynthetic AgNPs on superficial fungi have rarely been reported. The objectives of this study were to isolate endophytic fungi from medicinal plants for the biosynthesis of AgNPs and to assess the inhibitory effects of these AgNPs on superficial fungi as well as their biosafety toward skin cells. The endophytic fungal strain ZMS27, capable of biosynthesizing AgNPs, was isolated from medicinal plant Anemarrhena asphodeloides and identified as Clonostachys rosea. The UV‒visible spectroscopic measurements revealed a strong absorption peak at 340 nm, indicating the successful synthesis of the ZMS27-AgNPs. The AgNPs were well-dispersed, globular particles with an average diameter of 7.33 ± 0.18 nm, as determined by transmission electron microscopy (TEM) analysis. The FTIR analysis revealed that various functional molecules from C. rosea ZMS27 are involved in the synthesis of AgNPs. ZMS27-AgNPs significantly inhibited the growth of five superficial pathogenic fungi at minimal inhibitory concentration ranging from 1.56 to 25 µg·mL
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