Evidence map›Paper›PMID 40465006›Full record

ArticleInsights into imaging2025

Impaired right atrial function preceding right ventricular systolic dysfunction: clinical utility and long-term prognostic value in pulmonary hypertension.

Fan Yang, Yan Yan, Wang Jiang, Zhouming Wang, Caixin Wu, Qian Wu, Yuanlin Deng, Yamin Du, Zhenwen Yang, Zhang Zhang and 1 more

Erratum issuedAbstract read
In one paragraph

Article in Insights into imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Right Heart Diastology, Where Are We Now?Circulation research · 2026
    Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Fan Yang *Department of Radiology, Tianjin Medical University General Hospital, Tianjin, China.
Yan Yan *Department of Radiology, Tianjin Medical University General Hospital, Tianjin, China.
Wang JiangDepartment of Radiology, Tianjin Medical University General Hospital, Tianjin, China.
Zhouming WangDepartment of Cardiology, Tianjin Medical University General Hospital, Tianjin, China.
Caixin WuDepartment of Radiology, Tangshan Maternal and Child Health Hospital, Hebei, China.
Qian WuDepartment of Radiology, Tianjin Medical University General Hospital, Tianjin, China.
Yuanlin DengDepartment of Radiology, Tianjin Medical University General Hospital, Tianjin, China.
Yamin DuDepartment of Radiology, Tianjin Medical University General Hospital, Tianjin, China.
Zhenwen YangDepartment of Cardiology, Tianjin Medical University General Hospital, Tianjin, China. yzwmd@hotmail.com.
Zhang ZhangDepartment of Radiology, Tianjin Medical University General Hospital, Tianjin, China. filea1249@sina.com.
Dong LiDepartment of Radiology, Tianjin Medical University General Hospital, Tianjin, China. dr_lidong@163.com.ORCID http://orcid.org/0000-0002-0331-6022

Funding

National Natural Science Foundation of China 82271937National Natural Science Foundation of China 82471927Natural Science Foundation of Tianjin Municipality 22JCZDJC00500Tianjin Key Medical Discipline (Specialty) Construction Project TJYXZDXK-001AWu Jieping Medical Foundation 320.6750.2022-3-5
6 · The paper itself

Abstract

objectivesPulmonary hypertension (PH) in patients with right ventricular systolic dysfunction (RVSD) is associated with a poor prognosis. This study assessed the characteristics of right atrial (RA) function using cardiac magnetic resonance feature tracking (CMR-FT) before RVSD onset and evaluated the long-term prognostic significance of these characteristics. MATERIALS AND

methodsA total of 96 PH patients, including 36 without RVSD (PH-nonRVSD) and 60 with RVSD (PH-RVSD), were compared to 20 healthy controls (HCs). The RA reservoir, conduit, booster pump functions, and the right ventricular global longitudinal strain (RVGLS) were evaluated. Ventricular morphological and functional parameters of the RA and right ventricle (RV) were also acquired.

resultsCompared with HCs, both RA reservoir and conduit functions were significantly reduced (p

conclusionsRA function can detect right heart dysfunction prior to RVSD and monitor disease progression in patients with PH. Moreover, RA reservoir function independently predicts long-term prognosis. CRITICAL RELEVANCE STATEMENT: Impairment of right atrial (RA) function, assessed by cardiac magnetic resonance feature tracking (CMR-FT), in pulmonary hypertension (PH) patients is sensitive in detecting right-sided heart dysfunction before right ventricular systolic dysfunction and can be utilized to monitor disease progression and long-term prognosis. KEY POINTS: RA function is sensitive in detecting early right heart dysfunction in PH patients. The disease progression of PH can be monitored by assessing RA function. RA function can serve as a tool for predicting long-term prognosis.

Indexed as

Magnetic resonance imagingPrognosisPulmonary hypertensionRight atrial functionRight ventricular dysfunction

Identifiers

PMID40465006
PMCPMC12137862

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