Evidence map›Paper›PMID 40464999›Full record

ArticleJournal of robotic surgery2025

Risk factors and risk-stratification model of biochemical failure in patients with positive surgical margin after robot-assisted radical prostatectomy.

Yuta Yamada, Yuji Hakozaki, Naohiro Makise, Jimpei Miyakawa, Yoichi Fujii, Naoki Kimura, Kazuma Sugimoto, Jun Kaneko, Kazuki Maki, Taketo Kawai and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of robotic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yuta YamadaDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Yuji HakozakiDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan. yhakozaki11012@gmail.com.ORCID http://orcid.org/0000-0003-3137-2475
Naohiro MakiseDivision of Surgical Pathology, Chiba Cancer Center, Chiba-Shi, Chiba, Japan.
Jimpei MiyakawaDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Yoichi FujiiDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Naoki KimuraDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Kazuma SugimotoDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Jun KanekoDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Kazuki MakiDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Taketo KawaiDepartment of Urology, International University of Health and Welfare Ichikawa Hospital, Ichikawa-Shi, Chiba, Japan.
Shigenori KakutaniDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Aya NiimiDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Jun KameiDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Satoru TaguchiDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Daisuke YamadaDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Haruki KumeDepartment of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was investigating the risk factors of biochemical failure in cases with positive surgical margins after robot-assisted radical prostatectomy (RARP). We identified 630 cases of RARP that had been performed in a single institution from November 2011 to December 2017. A total of 145 cases showed positive surgical margin after RARP. After excluding patients that had undergone adjuvant therapies (androgen deprivation or radiation), 114 cases were evaluated. Clinical and pathological parameters were investigated in this cohort and were analyzed to identify factors predicting biochemical failure. Subsequently, we developed a risk classification based on these risk factors. The median values of PSA, age, preoperative prostate volume, were 67 (internal quartile range [IQR]: 65-72) years, 9.3 (6.5-12.0) ng/mL, and 37 (25-45) cm

Indexed as

Margins of ExcisionProstatectomyProstatic NeoplasmsRobotic Surgical ProceduresAgedHumansMaleMiddle AgedProstateProstate-Specific AntigenRetrospective StudiesRisk AssessmentRisk FactorsTreatment FailureProstate-Specific AntigenBiochemical recurrencePositive surgical marginRisk factorsRobot-assisted radical prostatectomy

Identifiers

PMID40464999
PMCPMC12137452

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.