Evidence map›Paper›PMID 40464937›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Characterising patients undergoing surgery for lumbar spinal stenosis associated neurogenic claudication in the UK: what does the British Spinal Registry tell us?

Lianne Wood, Rebecca Hunter, Esther Williamson, Khalid M Salem, Opinder Sahota, Bethan E Phillips, Paul Hendrick, Sarah E Lamb

Abstract read
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lianne WoodUniversity of Exeter, Exeter, UK. l.wood2@exeter.ac.uk.
Rebecca HunterUniversity of Exeter, Exeter, UK.
Esther WilliamsonUniversity of Exeter, Exeter, UK.
Khalid M SalemNottingham University Hospitals NHS Trust, Nottingham, UK.
Opinder SahotaNottingham University Hospitals NHS Trust, Nottingham, UK.
Bethan E PhillipsUniversity of Nottingham, Nottingham, UK.
Paul HendrickUniversity of Nottingham, Nottingham, UK.
Sarah E LambUniversity of Exeter, Exeter, UK.

Funding

Programme Development Grants NIHR205671
6 · The paper itself

Abstract

purposeSurgery for lumbar spinal stenosis (LSS) has a variable outcome with many not returning to pre-condition activity levels. We aimed to explore the (1) baseline characteristics of UK patients undergoing surgery, and (2) association of patient characteristics with a clinically important improvement in the 6-month Oswestry Disability Index (ODI) in a population defined by previously developed LSS criteria.

methodsWe used data from the British Spinal Registry (BSR) (2012-2023). Anonymised data included demographics, patient reported outcome measures (PROMs) (ODI; visual analogue scale (VAS) for back and leg pain); quality of life (EQ-5D)) at baseline, and 6-weeks and 6-months post-surgery, surgical procedure, surgery duration and intra-operative blood loss. We used descriptive and multivariate analyses to estimate the association between variables and the minimum clinically important difference (MCID) (30% improvement from baseline) in 6-month disability (ODI). MCIDs define the smallest benefit of value to patients. We explored differences in baseline values between 6-month responders and the total database, and between primary and revision surgery.

resultsIn 6801 patients sampled from the BSR the mean age was 70.5 (SD 9.1), 51% (3452/6794) were female, and most were from higher socioeconomic areas (mean Index of Multiple Deprivation rank 84.3, SD 38.8). Preoperatively most had severe disability (ODI 48.7, SD 17.5), moderate leg (VAS 7.0, SD 2.4) and back pain (VAS 6.3, SD 2.5). Proportionally 58% (1160/2008) of the 6-month responders achieved the MCID in ODI. Higher baseline back pain intensity (odds ratio (OR) 0.9, 95%CI 0.9, 0.9), revision surgery (OR 0.5 95%CI 0.3, 0.8), higher 6-week leg pain intensity (OR 0.9, 95%CI 0.8, 1.0) and severe 6-week disability (OR 0.3, 95%CI 0.2, 0.5) reduced the odds of achieving the MCID in 6-month ODI.

conclusionsPatients undergoing surgery in the UK are severely disabled prior to surgery. The available data suggests that 42% of UK patients do not achieve a clinically important improvement in 6-month disability.

Indexed as

Intermittent ClaudicationLumbar VertebraeRegistriesSpinal StenosisAgedAged, 80 and overDecompression, SurgicalDisability EvaluationFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresQuality of LifeTreatment OutcomeUnited KingdomAssociationCohortLumbar spinal stenosisPredictorsRegistrySurgery

Identifiers

PMID40464937
PMCPMC12367967

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.