Evidence map›Paper›PMID 40464917›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Does obstructive sleep apnoea surgery improve perceived insomnia severity in patients suffering from co-morbid insomnia and sleep apnoea (COMISA)?

Mohamed S Rashwan, Aranee Thirukketheesparan, Katherine Haworth, Asma Awad, Aaron Trinidade, Amro Hassaan

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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6 authors.

Mohamed S RashwanDepartment of Otolaryngology, Queen's Hospital, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, UK. m_salaheldin@med.suez.edu.eg.ORCID http://orcid.org/0000-0001-8233-196X
Aranee ThirukketheesparanDepartment of Otolaryngology, Queen's Hospital, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, UK.
Katherine HaworthDepartment of Psychiatry, North East London NHS Foundation Trust, London, UK.
Asma AwadDepartment of Otolaryngology, Queen's Hospital, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, UK.
Aaron TrinidadeDepartment of Otolaryngology, Southend Hospital, Mid & South Essex NHS Foundation Trust, Southend-On-Sea, UK.
Amro HassaanDepartment of Otolaryngology, Queen's Hospital, Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effect of obstructive sleep apnoea (OSA) surgery on insomnia in patients with co-morbid insomnia and sleep apnoea (COMISA).

methodsA retrospective interventional study was conducted on fifty consecutive adult patients with OSA who underwent surgery for OSA. Outcome measures included the Insomnia Severity Index (ISI) and the following polysomnography (PSG) indices: apnoea-hypopnea index (AHI), oxygen saturation index (ODI), lowest oxygen saturation (LOS) and Epworth Sleepiness Score (ESS) before treatment and at 4 months post-operatively.

resultsIn our study, 36% of the patients had clinical insomnia (ISI score > 15) prior to surgery. Following OSA surgery, there was an average improvement in the total ISI scores from 19.82 to 5.65 (p < 0.05). One patient continued to have moderate to severe clinical insomnia. Overall OSA parameters following surgery showed AHI decreased from 33.38 ± 23.76 to 18.37 ± 22.94 (p < 0.05); ODI reduced from 30.85 ± 22.37 to 16.77 ± 21.73 (p < 0.05); LOS significantly increased from 74.42 ± 11.93 to 87.70 ± 7.59 (p < 0.05); ESS showed significant reduction from 10 ± 5.9 to 6.55 ± 5.18 (p < 0.05).

conclusionOur results showed a reduction in the insomnia scores of our COMISA subgroup and a significant post-operative improvement in ambulatory polysomograph variables. OSA and insomnia are strongly correlated and surgical treatment of OSA appears to be effective in reducing the insomnia burden in COMISA patients.

Indexed as

Sleep Apnea, ObstructiveSleep Initiation and Maintenance DisordersAdultAgedComorbidityFemaleHumansMaleMiddle AgedOxygen SaturationPolysomnographyRetrospective StudiesSeverity of Illness IndexTreatment OutcomeComorbid insomnia and sleep apnoea (COMISA)InsomniaInsomnia severity index (ISI)Obstructive sleep apneaObstructive sleep apnoea hypopnoea syndrome (OSAHS)OSA surgery

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.