Evidence map›Paper›PMID 40464866›Full record

ArticleThe Saudi dental journal2025

Exploring research hotspots and trends in periodontal regeneration from 2000 to 2023: a bibliometric analysis.

Jingchao Hu, Li Zhao, Xu Liu, Ling Xu, Han Zhao

Abstract read
In one paragraph

Article in The Saudi dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jingchao Hu *Department of Periodontics, Beijing Stomatological Hospital, School of Stomatology, Capital Medical University, Fan Jia Cun Road 9, Beijing, 100071, China.
Li Zhao *Department of Prosthodontics, Stomatological Hospital, Chongqing Medical University, Chongqing, 400015, China.
Xu LiuLaboratory of Tissue Regeneration and Immunology and Department of Periodontics, Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Capital Medical University, BeijingBeijing, China.
Ling XuDepartment of Prosthodontics, Stomatological Hospital, Chongqing Medical University, Chongqing, 400015, China.
Han ZhaoDepartment of International Medical Service, Beijing Stomatological Hospital, School of Stomatology, Capital Medical University, Fan Jia Cun Road 9, Beijing, 100071, China. z75301704@163.com.ORCID http://orcid.org/0000-0003-0526-610X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this bibliometric analysis was to evaluate research interest and trends in the field of periodontal regeneration from 2000 to 2023. An online search was conducted in the Web of Science Core Collection database to retrieve relevant studies published between 2000 and 2023. Statistical analysis and scientific mapping were performed using R language, CiteSpace, and VOSviewer to examine journals, countries, institutions, authors, keywords, and citations. From 2000 to 2023, a total of 1,932 papers were published, and the number of papers and citations showed consistent growth. The Journal of Periodontology had the highest number of publications and citations. China and the United States were the most productive countries, while contributions from developing nations in Asia and Africa, as well as several Chinese dental institutions, increased significantly. Sculean A was the most prolific author and established a global collaboration network. Seventy-seven high-frequency keywords were identified, with recent trends highlighting 3D printing, hydrogels, and electrospinning. Among the top 25 papers with the strongest citation bursts, eight focused on stem cells and six on enamel matrix derivatives (EMD)/enamel matrix proteins (EMPs), ranking first and second, respectively. Additionally, 15 reference clusters were observed, with melt electrowriting (#0), tissue engineering (#4), exosome (#5), and periodontitis (#7) gaining prominence since 2013, indicating sustained research interest. Periodontal regeneration has remained a prominent research topic. China and the United States are the leading contributors, while developing countries in Asia and Africa have played an increasingly important role in recent years. Research hotspots have evolved dynamically, driven by advancements in biomaterials. Current key themes include hydrogels, 3D printing, electrospinning, melt electrowriting and exosomes; however, clinical evidence supporting these techniques remains limited.

Indexed as

BibliometricsGuided tissue regenerationMappingPeriodontal regeneration

Identifiers

PMID40464866
PMCPMC12137857

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.