SynthesisAesthetic plastic surgery2025
Impact of Septal Extension Graft on Functional and Esthetic Outcomes in Patients with Severe Nasal Deviation: A Systematic Review and Meta-analysis.
Synthesis in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- New Insights into the Role of Columellar Strut and Septal Extension Graft: A Comparative Review of Long-Term Outcomes.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere nasal deviation is a complex deformity affecting the esthetics and functionality of the nose, creating an asymmetrical appearance due to septal misalignment. Advances in nasal anatomy and biomechanics have led to the use of grafting materials, such as septal extension grafts. However, its efficacy remains inconclusive. This study investigated the impact of septal extension grafts on the functional and esthetic outcomes in severe nasal deviation.
methodsA literature search was conducted using PubMed, Google Scholar, MEDLINE, Web of Science, and the Cochrane Central Register of Controlled Trials (CENTRAL) from inception to date. Studies were selected based on predefined eligibility criteria, and the Cochrane Risk of Bias in Non-randomized Studies of Interventions (ROBINS-I) tool was used to assess bias risk.
resultsThe search yielded 1,242 records, of which 18 were included for 1763 patients. Most studies reported statistically significant improvements in Nasal Obstruction Symptom Evaluation (NOSE) scores and nasal symmetry. Improved esthetic outcomes and patient satisfaction were observed after septal extension graft procedures. Patients also experienced increased tip projection and reduced dorsal deviation, with p<0.001 in most studies. The revision rate was significantly lower (OR 0.02, 95% CI 0.00-0.09, p<0.00001). However, slight complications were observed, including tip stiffness (affecting up to 45.5% of patients) and tip deviation (11.4%).
conclusionPatients with severe nasal deviation consistently improved functional and esthetic outcomes, experienced favorable patient satisfaction, and achieved long-term stability. However, careful consideration is essential due to reported complications and occasional revision surgeries. LEVEL OF EVIDENCE III: This review includes well-designed cohort and case-control studies, which provide moderate-quality evidence on the efficacy of septal extension grafts in treating severe nasal deviation. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.