Evidence map›Paper›PMID 40464724›Full record

Observational studyJournal of vascular surgery2025

Hospital setting of endovascular repair influences procedural outcomes in blunt traumatic aortic injury.

John H Cabot, Micaella Zubkov, Lisa M Knowlton, Anna Romagnoli, David S Kauvar, PROspective Observational Vascular Injury Treatment Study Investigators

Abstract readObservational StudyMulticenter StudyComparative Study
In one paragraph

Observational study in Journal of vascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

John H CabotDivision of Vascular Surgery, Stanford University School of Medicine, Palo Alto, CA; Stanford Cardiovascular Institute, Stanford University School of Medicine, Palo Alto, CA.
Micaella ZubkovDepartment of Surgery, University of Colorado, Denver, CO.
Lisa M KnowltonDepartment of Surgery, Stanford University School of Medicine, Palo Alto, CA.
Anna RomagnoliR. Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, MD.
David S KauvarDivision of Vascular Surgery, Stanford University School of Medicine, Palo Alto, CA. Electronic address: dkauvar@stanford.edu.
PROspective Observational Vascular Injury Treatment Study Investigators

Funding

T32 Training Program in Mechanisms and Innovation in Vascular DiseaseT32HL098049 · NHLBI · STANFORD UNIVERSITY · PI Nicholas James Leeper, Philip S Tsao · 2010 to 2026
$6.3M
Increasing Medicaid Acquisition and Sustainment among the UninsuredR01MD018773 · NIMHD · STANFORD UNIVERSITY · PI Lisa Marie Knowlton · 2023 to 2026
$2.8M
NHLBI NIH HHS T32 HL098049NIMHD NIH HHS R01 MD018773
6 · The paper itself

Abstract

backgroundThoracic endovascular aortic repair (TEVAR) has become the mainstay of treatment for blunt thoracic aortic injuries (BTAI) over open repair. Since the arrival of TEVAR, hybrid operating rooms have emerged as highly specialized environments equipped to streamline endovascular and open cases. Procedure characteristics and outcomes may vary when TEVAR is performed in the setting of a standard operating room with a portable C-Arm vs in a hybrid operating room or interventional radiology (IR) suite with a fixed imaging system. The purpose of this study was to compare clinical characteristics and outcomes of TEVAR for BTAI across these settings. We hypothesize that cases performed with a C-Arm would lead to higher rates of complications.

methodsThe PROOVIT registry (PROspective Observational Vascular Injury Treatment) captures trauma-specific outcomes related to vascular injury across 14 trauma centers in the United States. The registry was queried for BTAI undergoing TEVAR from 2012 to 2021. Cases were categorized as having been performed in a standard operating room with portable C-Arm imaging (C-Arm), or in a fixed imaging suite (hybrid room [Hybrid] or IR). Procedural characteristics and complications (arterial access, reintervention, stroke) were collected and compared using univariate analyses.

resultsPROOVIT contained 199 TEVAR for BTAI: 82 C-Arm, 75 Hybrid, and 42 IR cases. There was no clear temporal trend in the setting TEVAR was performed. Demographics and mechanism of injury were similar between groups; Hybrid room procedures had higher median Injury Severity Score (ISS) (38; interquartile range [IQR], 14) than C-Arm (33; IQR, 15) and IR (29; IQR, 25; P = .02) and a higher proportion of cases with an Abbreviated Injury Scale head score of >3 (44% vs 28% C-Arm vs 24% IR; P = .06). Hybrid cases were most often delayed >6 hours from arrival (78% vs 48% vs 41%; P < .001), but C-Arm cases most frequently lasted >3 hours (34% vs 12% Hybrid vs 15% IR; P = .002). Use of C-Arm (P = .03) and time to TEVAR of <6 hours (P = .04) were predictors of complications. All strokes (n = 3) occurred in C-Arm cases (P = .04).

conclusionsDespite technological advances, TEVAR for BTAI is still performed frequently in a standard operating room with C-Arm imaging, rather than with a fixed imaging system in a hybrid operating room or IR suite. C-Arm procedures take longer and have higher complication rates, including stroke. TEVAR for BTAI is conducted most safely using a fixed imaging system in a hybrid operating room setting.

Indexed as

Aorta, ThoracicBlood Vessel Prosthesis ImplantationEndovascular ProceduresOperating RoomsTrauma CentersVascular System InjuriesWounds, NonpenetratingAdultAgedFemaleHumansMaleMiddle AgedPostoperative ComplicationsProspective StudiesRegistriesBlunt traumatic aortic injuryHybrid operating roomOperating settingThoracic endovascular aortic repairTrauma

Identifiers

PMID40464724
PMCPMC13056249

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.