Evidence map›Paper›PMID 40464530›Full record

Trial reportEuropean endodontic journal2025

Anesthetic Efficacy, Injection Pain and Pulse-rate Effect of Needle-free Injection in Pulpal Anesthesia of Maxillary Premolars with Irreversible Pulpitis: Randomised Clinical Study.

Hatice Sağlam, Ertuğrul Karataş

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European endodontic journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07498621 (Assessment of Maxillary Local Anesthesia Infiltration Efficiency and Adult Patient Satisfaction), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07498621 nacompletednot on this map

Assessment of Maxillary Local Anesthesia Infiltration Efficiency and Adult Patient Satisfaction: Needle-free Jet vs Conventional Syringe in Simple Tooth Extraction in a Single-blinded, Randomized Controlled Trial

TypeinterventionalSponsorKing Abdulaziz UniversityRan2025 to 2025Enrolled10ConditionsPain Perception of the New DeviceArmsneedle-free anesthesia jet (Comfort-in™), Conventional dental syringe injection
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hatice SağlamDepartment of Endodontics, Biruni University, Faculty of Dentistry, Istanbul, Türkiye.
Ertuğrul KarataşDepartment of Endodontics, Atatürk University, Faculty of Dentistry, Erzurum, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to compare the pain perception associated with the needle-free system (Comfort-In™) and the standard needle injection method during root canal treatments in adults.

methodsForty-four maxillary premolar teeth of the patients that applied to university for treatment and needed endodontic treatment were included in the study. Patients were anesthetized with two different injection methods; needle-free injection and conventional dental injection. In both groups, oxygen saturation and pulse measurements of the patients were recorded at 30-second intervals for 2 minutes before anesthesia and 4 minutes after anesthesia. Pain during the injection and opening of the access cavity preparation was recorded according to Visual Analog Scale (VAS). The data were analyzed according to a statistical program.

resultsIn this study, a significant difference was found between the groups in terms of pain during anesthesia administration and the access cavity preparation (p<0.001). There were no significant differences in terms of gender and age (p>0.05). There was no significant difference between the groups in terms of oxygen saturation and pulse values before and after treatment (p>0.05).

conclusionNeedle-free injection makes the treatment more comfortable for patients with injection fear and anxiety, making the procedure easier for the physician and the patient. (EEJ-2024-12-197).

Indexed as

Anesthesia, DentalAnesthetics, LocalBicuspidHeart RateInjectionsPainPulpitisAdultFemaleHumansMaleMaxillaNeedlesPain MeasurementRoot Canal TherapyYoung AdultAnesthetics, Local

Identifiers

PMID40464530
PMCPMC12102772

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.