Evidence map›Paper›PMID 40464379›Full record

ArticleRevista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia2025

[Epidemiological characteristics of patients with carbapenemase-producing NDM Enterobacterales isolates in a high-complexity hospital].

Cristina María Artiles-León, Sarita Rodríguez-Restrepo, Ivonne Andrea Torres-Jiménez, María de Las Delicias Quintana-Estellés, Esther Viedma-Moreno, Pilar Arrazola-Martínez, Felisa Jaén-Herreros, Inmaculada Sanz-Gallardo, Esther Suárez-García, Ana Craviotto-Vallejo and 1 more

Abstract readEnglish Abstract
In one paragraph

Article in Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cristina María Artiles-LeónHospital Universitario 12 de Octubre, Madrid, España.ORCID 0009-0003-1617-5403
Sarita Rodríguez-RestrepoHospital Universitario 12 de Octubre, Madrid, España.ORCID 0000-0002-1916-0747
Ivonne Andrea Torres-JiménezHospital Universitario 12 de Octubre, Madrid, España.ORCID 0000-0003-3829-9565
María de Las Delicias Quintana-EstellésHospital Universitario 12 de Octubre, Madrid, España.ORCID 0009-0008-7712-1077
Esther Viedma-MorenoHospital Universitario 12 de Octubre, Madrid, España.ORCID 0000-0003-3126-2735
Pilar Arrazola-MartínezHospital Universitario 12 de Octubre, Madrid, España.ORCID 0009-0000-0649-4513
Felisa Jaén-HerrerosHospital Universitario 12 de Octubre, Madrid, España.
Inmaculada Sanz-GallardoHospital Universitario 12 de Octubre, Madrid, España.
Esther Suárez-GarcíaHospital Universitario 12 de Octubre, Madrid, España.ORCID 0009-0009-0415-7762
Ana Craviotto-VallejoHospital Universitario 12 de Octubre, Madrid, España.ORCID 0000-0002-0947-5286
Sara de Miguel-GarcíaHospital Universitario 12 de Octubre, Madrid, España. sarade.miguel@salud.madrid.org.ORCID 0000-0003-2385-2698

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCarbapenemase-producing Enterobacteriaceae (CPE) of the New Delhi metallo-β-lactamase (NDM) type are a growing public health concern due to their rapid dissemination, widespread antimicrobial resistance and associated increase in morbidity and mortality. The aim of this study was to describe the epidemiological characteristics of patients with NDM-type CPE (NDM-CPE) isolates.

methodsA descriptive study of patients with at least one CPE-NDM isolate between December 1, 2022, and December 31, 2023. Demographic and clinical evolution data were collected from electronic medical records.

resultsNDM-CPE were identified in 77 patients, 87% of whom were adults and 75.3% were male. Thirty-two-point five percent were immunosuppressed. A total of 84.4% required hospital admission (60% in ICU) and 66.2% underwent surgery. The median time between admission and the first microbiological isolation of NDM-CPE was 18 days (RIC: 4-32 days). The most frequent microorganism was

conclusionsEarly identification of carriers, strengthening epidemiological and molecular surveillance, and prompt implementation of control measures are essential to interrupt transmission chains and protect the most vulnerable patients.

Indexed as

Bacterial Proteinsbeta-LactamasesCarbapenem-Resistant EnterobacteriaceaeEnterobacteriaceaeEnterobacteriaceae InfectionsAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsFemaleHospitalsHumansMaleMiddle AgedRetrospective StudiesAnti-Bacterial AgentsBacterial Proteinsbeta-lactamase NDM-1beta-LactamasescarbapenemaseCarbapenemaseCPEMultiresistantNDM

Identifiers

PMID40464379
PMCPMC12257181

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.