Evidence map›Paper›PMID 40464360›Full record

ArticleACS biomaterials science & engineering2025

Imaging Oxygen Concentrations in Bone Scaffolds during Cellular Activity and Fluid Perfusion.

Hannu Välimäki, Karim Ameziane, Sriparna Bhattacharya, Jonathan Massera, Pasi Kallio, Jeffrey N Anker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS biomaterials science & engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hannu VälimäkiMicro- and Nanosystems Research Group, Faculty of Medicine and Health Technology, Tampere University, Tampere 33014, Finland.ORCID 0000-0002-9611-1711
Karim AmezianeMicro- and Nanosystems Research Group, Faculty of Medicine and Health Technology, Tampere University, Tampere 33014, Finland.
Sriparna BhattacharyaDepartment of Physics and Astronomy, Clemson University, Clemson, South Carolina 29634, United States.
Jonathan Massera3Bs: bioceramics, bioglasses and biocomposites, Faculty of Medicine and Health Technology, Tampere University, Tampere 33014, Finland.ORCID 0000-0002-1099-8420
Pasi KallioMicro- and Nanosystems Research Group, Faculty of Medicine and Health Technology, Tampere University, Tampere 33014, Finland.ORCID 0000-0002-2890-6782
Jeffrey N AnkerDepartments of Chemistry and Bioengineering, Clemson University, Clemson, South Carolina 29634, United States.ORCID 0000-0002-9544-2367

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing bone replacement scaffolds has been a driving ambition of regenerative medicine. Although great progress has been achieved for small scaffolds, the real clinical need is for large scaffolds >5 mm. Oxygenating these scaffolds is challenging, as slow diffusion rates lead to necrotic regions in the scaffold core. In this work, we modulate

Indexed as

Bone and BonesOxygenTissue ScaffoldsPerfusionSaccharomyces cerevisiaeOxygenbioglassBone scaffoldsluminescenceoxygen imagingperfusion

Identifiers

PMID40464360
PMCPMC12264768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.