Evidence map›Paper›PMID 40464057›Full record

ArticleJournal of the American Chemical Society2025

All-Heteroatom-Substituted Carbon Spiro Stereocenters: Synthesis, Resolution, Enantiomeric Stability, and Absolute Configuration.

Olivier Viudes, Céline Besnard, Alexander F Siegle, Oliver Trapp, Thomas Bürgi, Gennaro Pescitelli, Jérôme Lacour

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Enantioselective Access to Trifluoromethylated Spirocyclopropyl Heterocycles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Olivier Viudes
Céline BesnardLaboratory of Crystallography, University of Geneva, Quai Ernest Ansermet 24, 1211 Geneva 4, Switzerland.ORCID 0000-0001-5699-9675
Alexander F SiegleDepartment of Chemistry, Ludwig-Maximilians-University Munich, Butenandtstr. 5-13, Munich 81377, Germany.
Oliver TrappDepartment of Chemistry, Ludwig-Maximilians-University Munich, Butenandtstr. 5-13, Munich 81377, Germany.ORCID 0000-0002-3594-5181
Thomas BürgiDepartment of Physical Chemistry, University of Geneva, Quai Ernest Ansermet 30, 1211 Geneva 4, Switzerland.ORCID 0000-0003-0906-082X
Gennaro PescitelliDipartimento di Chimica e Chimica Industriale, University of Pisa, Via G. Moruzzi 13, 56124 Pisa, Italy.ORCID 0000-0002-0869-5076
Jérôme LacourORCID 0000-0001-6247-8059

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chiral tetra-heterosubstituted methanes (i.e., tetraoxa and azatrioxa carbon spiro stereocenters) are synthesized under CpRu catalysis, using cyclic carbonates and carbamates as substrates and α-diazo-β-ketoesters as reagents. Single enantiomers, isolated by chiral stationary phase chromatography, display chiroptical properties, from

Identifiers

PMID40464057
PMCPMC12200235

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.