ArticleJournal of dental research, dental clinics, dental prospects2025
Management of gingival hyperpigmentation using microneedling with ascorbic acid vs. scalpel technique: A comparative split-mouth study.
Article in Journal of dental research, dental clinics, dental prospects, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Comparative Evaluation of Injectable Platelet-Rich Fibrin with and Without Microneedling in Periodontal Regeneration: A Prospective Split-Mouth Clinical Study.Biomedicines · 2026Article
- Clinical and patient-reported outcomes of microneedling with ascorbic acid versus scalpel technique for gingival depigmentation: A randomized clinical trial.Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: In enhancing smile aesthetics, managing gingival hyperpigmentation has become increasingly important. Gingival hyperpigmentation can often affect individuals psychologically, prompting many individuals to seek treatment. Microneedling (MN) is emerging as a popular solution for minimizing gingival hyperpigmentation through a minimally invasive approach. In contrast, the scalpel technique is an established surgical intervention to remove pigmented tissue directly. This study investigated the effectiveness of these two techniques in terms of clinical and patient-related outcomes. Methods: This randomized control clinical study included 20 subjects with hyperpigmentation in both maxillary and mandibular arches. One arch of each subject was randomly allocated to MN using the coin toss method, and the other arch was assigned to the scalpel technique. Intraoperative bleeding, postoperative pain scores, wound healing index, Dummett oral pigmentation index (DOPI), and Hedin melanin index (HMI) were evaluated. Results: MN showed significantly better results in terms of pain, bleeding scores, DOPI, and HMI ( Conclusion: Being a gold standard, the scalpel technique offers precision but is accompanied by more bleeding and less patient compliance due to its invasiveness. Conversely, the MN technique emerges as an advanced technique, demonstrating less pain and bleeding, thus enhancing patient comfort and overall satisfaction, aligning with the evolving preferences for minimally invasive dental procedures.
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