Evidence map›Paper›PMID 40463975›Full record

ArticleFrontiers in medicine2025

Global trends in typhoid and paratyphoid, and invasive non-typhoidal

Ke Shi, Tongdeng You

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Persistence of non-typhoidalFrontiers in microbiology · 2026
    Review
  6. Laboratory epidemiology ofOne health (Amsterdam, Netherlands) · 2025
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ke ShiDepartment of Clinical Laboratory, Fuzhou Changle District People's Hospital, Fuzhou, Fujian, China.
Tongdeng YouDepartment of Clinical Laboratory, Fuzhou Changle District People's Hospital, Fuzhou, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To assess the global burden of typhoid and paratyphoid fever, and Invasive Non-typhoidal Methods: Data were sourced from the Global Burden of Disease Study (GBD) 2021, focusing on age-standardized incidence rate (ASIR), mortality rate (ASMR), disability-adjusted life years rate (ASDR), and annualized percent change (EAPC). Results: From 1990 to 2021, the global burden of typhoid and paratyphoid fever decreased (EAPC = -4.15; 95% CI: -4.45 to -3.85). In contrast, the burden of iNTS showed a slow increasing trend (EAPC = 0.45; 95% CI: -0.32 to 1.22). The major epidemic trends were concentrated in regions with low and middle Socio-demographic Index (SDI). In high SDI regions, the age group most affected by deaths was 75 years and older, whereas in low SDI regions, particularly for typhoid and paratyphoid fever, deaths were more prevalent among children aged 0-14 years. Disability-adjusted life years (DALYs) and deaths due to multidrug-resistant Conclusion: While the global burden of typhoid and paratyphoid fever has declined, the burden of iNTS continues to rise slowly. The growing antimicrobial resistance of Salmonella further exacerbates the global disease burden.

Indexed as

antimicrobial resistanceDALYsincidenceInvasive Non-typhoidal Salmonellamortalitytyphoid and paratyphoid

Identifiers

PMID40463975
PMCPMC12129787

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.