Evidence map›Paper›PMID 40463969›Full record

ArticleFrontiers in medicine2025

Comparative study of effectiveness and safety between non-Descemet stripping endothelial keratoplasty and Descemet stripping endothelial keratoplasty for endothelial decompensation.

Minghai Huang, Guina Yin, Thuthuy Hoang, Zhifeng Wu, Jian Teng, Yanqing Liang, Zhuoyuan Zhang, Dongmei Wei

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Long-Term Endothelial Outcomes and Dislocation Risks in Small Versus Large Grafts for Descemet's Stripping Endothelial Keratoplasty.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Minghai HuangNanning Aier Eye Hospital, Nanning, China.
Guina YinNanning Aier Eye Hospital, Nanning, China.
Thuthuy HoangNanning Aier Eye Hospital, Nanning, China.
Zhifeng WuNanning Aier Eye Hospital, Nanning, China.
Jian TengNanning Aier Eye Hospital, Nanning, China.
Yanqing LiangNanning Aier Eye Hospital, Nanning, China.
Zhuoyuan ZhangNanning Aier Eye Hospital, Nanning, China.
Dongmei WeiNanning Aier Eye Hospital, Nanning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To compare the potential effectiveness and safety of non-Descemet stripping endothelial keratoplasty (nDSEK) and Descemet stripping endothelial keratoplasty (DSEK) in treating endothelial decompensation. Methods: A retrospective comparative analysis was conducted on patients with endothelial decompensation who underwent either nDSEK or DSEK procedures between August 2017 and January 2024. Participants were observed for a minimum duration of 12 months. The study documented key variables like best corrected visual acuity (BCVA), endothelial cell density (ECD), endothelial cell loss (ECL), and any issues that occurred during the follow-up period. Results: A total of 85 eyes from 85patients (nDSEK Conclusion: nDSEK eliminated the descemetorhexis step but yielded a comparable clinical outcome in effectiveness and safety compared to DSEK for treating endothelial decompensation.

Indexed as

Descemet stripping endothelial keratoplastyendothelial decompensationendothelial keratoplastynon-Descemet stripping endothelial keratoplastytreatment

Identifiers

PMID40463969
PMCPMC12129991

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.