Evidence map›Paper›PMID 40463935›Full record

ReviewFrontiers in neurology2025

Research trends and hotspots of central sleep apnea: a bibliometric analysis.

Yin-Chao Hao, Meng-Chu Zhu, Wei-Xuan Li, Jing-Jing Sha, Xue-Tong Dong, Song-Jun Wang, Chao-Long Lu

Abstract readReview
In one paragraph

Review in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yin-Chao Hao *Department of Neurobiology, Hebei Medical University, Shijiazhuang, China.
Meng-Chu Zhu *Department of Neurobiology, Hebei Medical University, Shijiazhuang, China.
Wei-Xuan LiUndergraduate of College of Forensic Medicine, Hebei Medical University, Shijiazhuang, China.
Jing-Jing ShaHebei Key Laboratory of Forensic Medicine, Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology, Collaborative Innovation Center of Forensic Medical Molecular Identification, College of Forensic Medicine, Chinese Academy of Medical Sciences, Hebei Medical University, Shijiazhuang, China.
Xue-Tong DongHebei Key Laboratory of Forensic Medicine, Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology, Collaborative Innovation Center of Forensic Medical Molecular Identification, College of Forensic Medicine, Chinese Academy of Medical Sciences, Hebei Medical University, Shijiazhuang, China.
Song-Jun WangHebei Key Laboratory of Forensic Medicine, Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology, Collaborative Innovation Center of Forensic Medical Molecular Identification, College of Forensic Medicine, Chinese Academy of Medical Sciences, Hebei Medical University, Shijiazhuang, China.
Chao-Long LuHebei Key Laboratory of Forensic Medicine, Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology, Collaborative Innovation Center of Forensic Medical Molecular Identification, College of Forensic Medicine, Chinese Academy of Medical Sciences, Hebei Medical University, Shijiazhuang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central sleep apnea (CSA), characterized by unstable ventilatory control during sleep, poses significant health risks, particularly in patients with cardiovascular comorbidities. This bibliometric analysis evaluated 1,687 CSA-related publications (2004-2025) from the Web of Science Core Collection. Annual publications surged post-2016, peaking in 2021 (115 articles), reflecting growing research interest. The U.S. and Germany dominated contributions, with American Journal of Respiratory and Critical Care Medicine as the top journal. Keyword analysis revealed three focal areas: CSA-heart failure interactions (e.g., mortality, ejection fraction), CSA mechanisms (e.g., hypercapnia, chemosensitivity), and clinical management (e.g., adaptive servo-ventilation, phrenic nerve stimulation). Emerging trends include pediatric CSA, pathophysiology, and AI-driven diagnostics. International collaboration and multidisciplinary approaches are critical for advancing CSA research. Limitations include database constraints and evolving literature. This study maps CSA research trends, highlights gaps, and guides future investigations into mechanisms, biomarkers, and personalized therapies.

Indexed as

bibliometrics analysiscentral sleep apneaCiteSpacepathophysiologyVOSviewer

Identifiers

PMID40463935
PMCPMC12129702

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.