Evidence map›Paper›PMID 40463857›Full record

ArticleJournal of inflammation research2025

The Association Between High-Sensitivity C-Reactive Protein and the Progression of Arteriosclerosis: The Kailuan Study.

Weizhe Li, Pei Liang, Xueliang Ma, Yanling Gao, Xiaoxin Bai, Shasha An, Xin Wang, Shuohua Chen, Shouling Wu

Abstract read
In one paragraph

Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. A Review on the Role of Oral Bacteria in Stroke.International journal of molecular sciences · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Weizhe Li *Department of Emergency Internal Medicine No. I, Handan Central Hospital, Handan, Hebei, 056001, People's Republic of China.ORCID 0009-0005-3997-0025
Pei Liang *Department of Intensive Care Rehabilitation, Handan Mingren Hospital, Handan, Hebei, 056001, People's Republic of China.
Xueliang MaDepartment of Emergency Internal Medicine No. I, Handan Central Hospital, Handan, Hebei, 056001, People's Republic of China.
Yanling GaoDepartment of Emergency Internal Medicine No. I, Handan Central Hospital, Handan, Hebei, 056001, People's Republic of China.
Xiaoxin BaiDepartment of Emergency Internal Medicine No. I, Handan Central Hospital, Handan, Hebei, 056001, People's Republic of China.
Shasha AnDepartment of General Medicine, Handan Central Hospital, Handan, Hebei, 056001, People's Republic of China.
Xin WangDepartment of Emergency Internal Medicine No. I, Handan Central Hospital, Handan, Hebei, 056001, People's Republic of China.
Shuohua ChenDepartment of Cardiology, Kailuan General Hospital, Tangshan, Hebei, 063001, People's Republic of China.
Shouling WuDepartment of Cardiology, Kailuan General Hospital, Tangshan, Hebei, 063001, People's Republic of China.ORCID 0000-0001-7095-6022

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the association between high-sensitivity C-reactive protein (hs-CRP) and the progression of arteriosclerosis. Methods: Using a prospective cohort study design, 11,577 participants from the Kailuan Study cohort who underwent at least two brachial-ankle pulse wave velocity (baPWV) examinations and met the inclusion criteria were included as the study subjects. Based on baseline hs-CRP levels, they were divided into three groups: hs-CRP <1 mg/L group, 1 mg/L≤hs-CRP≤3 mg/L group, and hs-CRP >3 mg/L group. Poisson regression analysis was employed for longitudinal comparison to assess the impact of different hs-CRP levels on baPWV≥1,400 cm/s. Results: (1) After a mean follow-up of 5.12 ± 2.84 years, the detection rates of baPWV≥1,400 cm/s at the end of follow-up were 28.54%, 33.36%, and 36.25% in the hs-CRP<1 mg/L (n=5,998), 1 mg/L≤ hs-CRP≤3 mg/L (n=4,101), and hs-CRP>3 mg/L (n=1,578) groups, respectively ( Conclusion: Elevated hs-CRP is an independent risk factor for arteriosclerosis progression.

Indexed as

arteriosclerosisbrachial-ankle pulse wave velocityhigh-sensitivity C-reactive proteinpoisson regression

Identifiers

PMID40463857
PMCPMC12132636

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.