Evidence map›Paper›PMID 40463832›Full record

ArticleOpen forum infectious diseases2025

Feasibility of Point-of-Care Urine Self-Testing to Measure Tenofovir Adherence and Predict Viral Suppression.

Renata Buccheri, Matthew A Spinelli, Megan J Heise, David V Glidden, Kevin Sassaman, Tyler Martinson, Hannah R Schmidt, Alexa B D'Angelo, Dustin T Duncan, Keith J Horvath and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Renata BuccheriDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0002-3217-5898
Matthew A SpinelliDivision of HIV, Infectious Diseases and Global Medicine, University of California San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0001-6368-8664
Megan J HeiseDivision of HIV, Infectious Diseases and Global Medicine, University of California San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0001-6651-2381
David V GliddenDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.
Kevin SassamanDivision of HIV, Infectious Diseases and Global Medicine, University of California San Francisco, San Francisco, California, USA.
Tyler MartinsonDepartment of Medicine, University of California San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0001-6750-3954
Hannah R SchmidtDepartment of Medicine, University of California San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0009-0005-5478-2997
Alexa B D'AngeloDepartment of Community Health and Social Sciences, CUNY Graduate School of Public Health and Health Policy, New York, New York, USA.
Dustin T DuncanDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York City, New York, USA.
Keith J HorvathSan Diego State University Department of Psychology, San Diego, California, USA.
Sabina HirshfieldDepartment of Medicine, STAR Program, State University of New York-Downstate Health Sciences University, Brooklyn, New York, USA.
Renessa S WilliamsUniversity of Miami School of Nursing and Health Studies, Coral Gables, Florida, USA.
Mallory O JohnsonDepartment of Medicine, Division of Prevention Science, University of California San Francisco, San Francisco, California, USA.
Christian GrovCity University of New York Graduate School of Public Health, New York, New York, USA.ORCID https://orcid.org/0000-0001-6871-3531
Adam CarricoDepartment of Health Promotion and Disease Prevention, Florida International University, Miami, Florida, USA.
Monica GandhiDivision of HIV, Infectious Diseases and Global Medicine, University of California San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0001-6674-5388

Funding

Developing a U.S. National Cohort to Improve Virologic Suppression among Stimulant-using Men Living with HIV.UG3DA058304 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CARRICO, ADAM WAYNE, GANDHI, MONICA · 2023 to 2024
$2.0M
Cannabis Use and Proximal Immune Dysregulation (CUPID)K23MD018337 · NIMHD · UNIVERSITY OF MIAMI CORAL GABLES · PI Renessa Williams · 2023 to 2026
$492k
NIDA NIH HHS UG3 DA058304NIMHD NIH HHS K23 MD018337NIMHD NIH HHS L60 MD019900
6 · The paper itself

Abstract

This study is the first to demonstrate the feasibility of at-home adherence monitoring using a point-of-care urine assay for tenofovir (TFV). Undetectable TFV is strongly associated with lower viral suppression (odds ratio, 0.19, 95% CI, 0.10-0.34;

Indexed as

adherenceantiretroviral therapypoint-of-care monitoringtenofovirviral suppression

Identifiers

PMID40463832
PMCPMC12131155

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.