Evidence map›Paper›PMID 40463778›Full record

ArticleArchives of rehabilitation research and clinical translation2025

Test-Retest Reliability and Minimal Detectable Change of Body Function Impairment and Activity Limitation Outcomes Using a Mechatronic Evaluation Designed for Inpatient Stroke Research.

Jane E Gyarmaty, Francesca S Abiusi, Natalie B Hoffman, Reem E Ibrahim, Emily R Linne, Sanjana Matta, Carli R Nissen, Maya A Sankaran, Alexandrea M Smith, Ana Maria Acosta and 1 more

Abstract read
In one paragraph

Article in Archives of rehabilitation research and clinical translation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jane E GyarmatyDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL.
Francesca S AbiusiDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL.
Natalie B HoffmanDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL.
Reem E IbrahimDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL.
Emily R LinneDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL.
Sanjana MattaDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL.
Carli R NissenDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL.
Maya A SankaranDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL.
Alexandrea M SmithDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL.
Ana Maria AcostaDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL.
Michael D EllisDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL.

Funding

Progressive Abduction Loading Therapy: A Phase IIb Stroke Rehabilitation Trial with Longitudinal TrackingR01HD096071 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ELLIS, MICHAEL D. · 2019 to 2023
$2.6M
NICHD NIH HHS R01 HD096071
6 · The paper itself

Abstract

Objective: To determine the test-retest reliability and minimal detectable change (MDC) scores for 7 precision measures examining upper extremity strength, reaching ability, and the expression of flexion synergy after stroke. The measurements relied on a mechatronic evaluation designed for time efficiency facilitating implementation in inpatient translational research. Design: Observational, analytical, cross-sectional study. Setting: University research laboratory. Participants: Twenty-five participants (N=25) >6 months poststroke with persistent upper extremity body function impairment and activity limitation were recruited using convenience sampling. Interventions: Not applicable. Main Outcome Measures: Shoulder abduction and elbow extension strength measured as a unit of torque (Nm); normalized reaching distance with the arm under 3 conditions: supported, against gravity, and against 50% of shoulder abduction strength; flexion synergy takeover; and emergence thresholds. Results: Twelve male and 13 female participants aged 56.4 ± 17.8 years with a mean time poststroke of 5.37 ± 7.55 years completed the study. The intraclass correlation coefficients for the outcome measures were as follows: shoulder abduction strength (0.963), elbow extension strength (0.983), supported reaching (0.982), reaching against gravity (0.968), reaching against 50% abduction strength (0.974), flexion synergy takeover (0.919), and flexion synergy emergence (0.949) thresholds. The MDC, overall mean, and standard deviation were calculated as follows: shoulder abduction strength (5.69 Nm, 24.44±10.67 Nm), elbow extension strength (5.66 Nm, 18.53±15.66 Nm), supported reaching (0.07, 0.91±0.20), reaching against gravity (0.15, 0.73±0.30), reaching against 50% abduction strength (0.13, 0.69±0.29), flexion synergy takeover (0.14, 0.91±0.17), and flexion synergy emergence (0.17, 0.56±0.27) thresholds. Conclusions: The mechatronic evaluation, although streamlined from more labor-intensive laboratory evaluations, demonstrates excellent (>0.90) test-retest reliability and MDC scores for 7 precision measures of upper extremity body function impairment (weakness and synergy) and activity limitation (reaching).

Indexed as

KinematicsPsychometricsRehabilitationStrokeUpper Extremity

Identifiers

PMID40463778
PMCPMC12128482

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.