ArticleJournal of bone and joint infection2025
Debridement, antimicrobial therapy, and implant retention (DAIR) as curative strategy for acute periprosthetic hip and knee infections: a position paper of the European Bone & Joint Infection Society (EBJIS).
Article in Journal of bone and joint infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Bacteriophages in Hip and Knee Periprosthetic Joint Infections: A Promising Tool in the Era of Antibiotic Resistance.Medical sciences (Basel, Switzerland) · 2025Pooled it
- Timing and microbiological profile influence long-term outcomes after debridement, antibiotics, and implant retention (DAIR) in acute hip periprosthetic joint infection.Archives of orthopaedic and trauma surgery · 2026Article
- The Mursa Protocol: A Novel Multimodal Antiseptic-Based DAIR Strategy for Early Hip Periprosthetic Joint Infection.Antibiotics (Basel, Switzerland) · 2026Article
- Article
- Microbiological Characteristics and Clinical Outcomes of Periprosthetic Infections Following Oncologic Megaprosthetic Reconstruction: A Retrospective Cohort Study.Pathogens (Basel, Switzerland) · 2026Article
- Early Prediction of 90-Day Periprosthetic Joint Infection After Hip Arthroplasty for Proximal Femur Fracture Using Machine Learning: Development and Temporal Validation of a Predictive Model.Journal of clinical medicine · 2026Article
- Machine Learning-Driven Probability Scoring Enhances Diagnostic Certainty and Reduces Costs in Suspected Periprosthetic Joint Infection.Diagnostics (Basel, Switzerland) · 2026Article
- High and strikingly early failure-rate following gram-negative periprosthetic joint infection - a retrospective cohort study on 72 cases.Archives of orthopaedic and trauma surgery · 2026Article
- Drug repurposing: a dual-mechanism antibiotic combats MRSA and its high resistant phenotypes.Frontiers in cellular and infection microbiology · 2026Article
- Socioeconomic burden of septic re-revision surgeries for periprosthetic joint infections in Europe - a comprehensive analysis of re-revision costs.Journal of bone and joint infection · 2026Article
- High failure rate inJournal of bone and joint infection · 2026Article
- Review of Recent Advances in Managing Periprosthetic Joint Infection After Total Knee Arthroplasty: DAIR Technique.Orthopedic research and reviews · 2026Review
- Sinus tract and purulence as clinical criteria for periprosthetic joint infection: diagnostic accuracy, microorganisms, and clinical outcomes.Journal of bone and joint infection · 2026Article
- AI-Generated Antibiotic Therapies for Acute Periprosthetic Joint Infections with Implant Retention in Comparison with an Interdisciplinary Team.Antibiotics (Basel, Switzerland) · 2025Article
- Diagnostic Performance of Serum Neutrophil-Lymphocyte and Serum Monocyte-Lymphocyte Ratios in Periprosthetic Joint Infection: A Comparative Meta-Analytic Review of 29 Studies.Journal of clinical medicine · 2025Review
- [Challenges in Arthroplasty : Contributions from the AE Sessions of the DKOU 2024].Orthopadie (Heidelberg, Germany) · 2025Article
- Clinical outcomes of an unplanned second debridement, antibiotics and implant retention (DAIR) procedure in acute postoperative prosthetic joint infections.International orthopaedics · 2025Article
- [Debridement, antimicrobial therapy, and implant retention for acute periprosthetic infections].Orthopadie (Heidelberg, Germany) · 2025Review
- Oritavancin a Therapeutic Option for Periprosthetic Joint Infections in Selected Cases: A Comprehensive Review.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Changing Incidence, Aetiology and Outcomes of Prosthetic Joint Infections: A Population-Based Study in Iceland.Journal of clinical medicine · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been shown that the outcome of a DAIR (debridement, antimicrobial therapy, and implant retention) procedure depends on multiple factors (e.g. infection type, host factors, clinical presentation, condition of surrounding soft tissue, causing pathogen, surgical technique, antimicrobial therapy); therefore, adequate patient selection is key for DAIR success. In this position paper, we discuss the most relevant factors influencing the outcome and define indications, contraindications, and risk factors for a DAIR procedure based on the most robust and most recently published data. Furthermore, we discuss the surgical technique in combination with systemic antimicrobial therapy in patients undergoing a DAIR procedure. This position paper may help reduce reinfection rates as well as the physical, psychological, and economic burden associated with periprosthetic joint infection (PJI). We believe that a reasonable outcome can be achieved with careful patient selection, a dedicated multidisciplinary team, and an appropriate surgical technique and antimicrobial therapy.
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Registered trials
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