Evidence map›Paper›PMID 40463612›Full record

ReviewMedical journal, Armed Forces India

Antimicrobial resistance: Current challenges and future directions.

Bipin Puri, Raju Vaishya, Abhishek Vaish

Abstract readReview
In one paragraph

Review in Medical journal, Armed Forces India. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. [Plasmid-mediated colistin resistance in pathogenic bacteria].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Pooled it
  2. Review
  3. EvaluatingParasite epidemiology and control · 2026
    Article
  4. Zinc oxide-bacteriophage synergistic combination for dual-mode antibacterial activity against multidrug-resistant Escherichia coli.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
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  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Eco-Friendly Synthesis ofBioinorganic chemistry and applications · 2026
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bipin PuriDirector Medical Services, Indraprastha Apollo Hospitals, Sarita Vihar, New Delhi, India.
Raju VaishyaProfessor & Senior Consultant Orthopaedic Surgeon, Indraprastha Apollo Hospitals, Sarita Vihar, New Delhi, India.
Abhishek VaishConsultant Orthopaedic Surgeon, Indraprastha Apollo Hospitals, Sarita Vihar, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The misuse of antibiotics has led to the emergence of antimicrobial resistance (AMR), particularly threatening critically ill patients reliant on these medications. This review explores the challenges of superbugs and AMR in critical care settings and highlights potential solutions. Methods: This narrative review used keywords like "antimicrobial resistance" and "superbugs" in PubMed, Scopus, and Google Scholar databases. Results: The overuse and misprescription of antibiotics contribute to developing superbugs, rendering traditional treatments ineffective in critical care. AMR in critical care leads to increased costs, extended hospital stays, and limited treatment options. Combating AMR requires a multifaceted approach, including antibiotic stewardship, research, and development of novel antibiotics and alternative therapies, and rigorous infection control measures. Public education and collaboration among stakeholders are crucial for effective strategies. Future success hinges on a paradigm shift toward antibiotic stewardship, innovation in antimicrobials, and infection control. Implementing legislation and antimicrobial stewardship (AMS) programs are necessary steps. Research gaps exist in understanding environmental factors influencing AMR. New classes of antibiotics, faster diagnostics, and optimized drug combinations are future directions. Global collaboration in research, surveillance, and policy development is paramount. Conclusion: AMR poses a significant threat to critical care. This review emphasizes the need for a multifaceted approach to protect the effectiveness of critical care interventions. Addressing these challenges and exploring potential solutions can ensure effective treatment for critically ill patients.

Indexed as

Antibacterial agentsCritical careDrug resistanceGlobal healthHumans

Identifiers

PMID40463612
PMCPMC12127279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.