Evidence map›Paper›PMID 40463598›Full record

ArticleMedical journal, Armed Forces India

Study on utility of GDH and prevalence of

Suby Kuriakose, Anuj Singhal, Kiran Kumar Kompella, Amul Kapoor, Ashish Bahal, Shilpa M Paul

Abstract read
In one paragraph

Article in Medical journal, Armed Forces India. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Infectious disease challenges in the post-COVID era.Medical journal, Armed Forces India
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Suby KuriakoseResident (Medicine), Army Hospital (R&R), New Delhi, India.
Anuj SinghalProfessor & Senior Advisor (Medicine), Army Hospital (R&R), New Delhi, India.
Kiran Kumar KompellaSenior Advisor (Medicine), Army Hospital (R&R), New Delhi, India.
Amul KapoorSenior Advisor (Medicine) & Med Oncologist, Army Hospital (R&R), New Delhi, India.
Ashish BahalProfessor & Senior Advisor (Pathology), Army Hospital (R&R), New Delhi, India.
Shilpa M PaulResident (Physiology), All India Institute of Medical Sciences, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Clostridium difficile ( Methods: This was a single center, prospective, diagnostic study conducted from July to Dec 2023. The study was carried out after obtaining clearance from the Institute Ethics Committee. As per a 2017 study done by Segar et al, keeping the tolerable error as 1.5 at 95% confidence interval, minimum sample size was found to be 200. Results: The prevalence of CDI among ICU patients was 6% and among diarrheic patients the prevalence was 20%. GDH showed a sensitivity and specificity of 100% with all cuture positive cases of CDI also showing GDH positivity. The length of ICU and hospital stay among CDI patients (28±17 days/56±17 days) was significantly longer compared to non CDI patients (11 ± 06 days/26 ± 18 days) (p-0.003). The overall hospital mortality among ICU patients with CDI patients was 33% as compared with 25% among those without CDI thus showing a statistically significant difference in mortality risk (p-0.030). Conclusion: It is concluded that there is a need for additional prevention and treatment studies in this setting. No correlation could be established between the choice or duration of antibiotic therapy and the development of CDI. Similarly no correlation could be established between the primary diagnosis for admission of the patient and development of CDI.

Indexed as

Choice of antibioticsClostridium difficile infectionDiarrheaGDH card testICU morbidity

Identifiers

PMID40463598
PMCPMC12127269

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.