Evidence map›Paper›PMID 40463497›Full record

ArticleResearch (Washington, D.C.)2025

Magnetic Cell-Mimetic Droplet Microrobots with Division and Exocytosis Capabilities.

Shimin Yu, Weiwei Zhang, Yongzhi Feng, Xiang Zhang, Chuanhua Li, Shengjun Shi, Haocheng Wang, Tianlong Li

Abstract read
In one paragraph

Article in Research (Washington, D.C.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shimin YuCollege of Engineering, Ocean University of China, Qingdao 266100, China.ORCID https://orcid.org/0000-0001-5255-6252
Weiwei ZhangSchool of Mechanical and Power Engineering, Zhengzhou University, Zhengzhou 450001, China.
Yongzhi FengState Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin 150001, China.
Xiang ZhangNational Center for International Joint Research of Micro-Nano Molding Technology, School of Mechanics and Safety Engineering, Zhengzhou University, Zhengzhou 450001, China.
Chuanhua LiState Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin 150001, China.
Shengjun ShiState Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin 150001, China.
Haocheng WangState Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin 150001, China.
Tianlong LiState Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin 150001, China.ORCID https://orcid.org/0000-0002-9483-457X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The first challenge in building a living robotic system inspired by life evolution is how to replicate the original form of life-the cell. However, current microrobots mimic cell motion control but fail to replicate the functional biological activities of cellular systems. Here, we propose a strategy that programs microparticle swarms encapsulated in droplets at an air/liquid interface to create cell-mimetic droplet microrobots with vitality by employing alternating magnetic fields. Through the design of algorithms and spontaneous interface waves, our collective system embodies reversible transitions between gas, chain, array, and disk-like collective modes, and emulates various complex activities of living cells in nature, including division and exocytosis. Based on these 2 capabilities learned from living cells, the cell-mimetic microrobots navigate the bile duct to the gallbladder under the guidance and control of magnetic fields, completing the drug release task. This cell-mimetic microrobots may provide a fundamental understanding of cellular life and pave the way for the construction of artificial living systems. Furthermore, they hold substantial potential for medical and environmental applications.

Identifiers

PMID40463497
PMCPMC12130622

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.