Evidence map›Paper›PMID 40463480›Full record

ArticleInfection and drug resistance2025

Synergy and Mechanism of the Action of the Combination of Essential Oils and Antibiotics Against Antibiotic-Resistant Food Borne Disease Bacteria in Burkina Faso.

Paul Sodéré, Marius K Somda, Luc Zongo, Henriette B Mihin, Iliassou Mogmenga, Agbémébia Y Akakpo, Mamoudou H Dicko

Abstract read
In one paragraph

Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. The genus Laggera: an extensive review of phytochemistry, pharmacology, clinical study, and chemical modification.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Effect of DifferentMolecules (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paul SodéréLaboratory of Microbiology and Microbial Biotechnology, Department of Biochemistry and Microbiology, University Joseph KI-ZERBO, Ouagadougou, 03 BP: 7021, Burkina Faso.ORCID 0009-0009-4895-9476
Marius K SomdaLaboratory of Microbiology and Microbial Biotechnology, Department of Biochemistry and Microbiology, University Joseph KI-ZERBO, Ouagadougou, 03 BP: 7021, Burkina Faso.
Luc ZongoHospital Saint Camille of Ouagadougou (HOSCO), Ouagadougou, 09 BP 444, Burkina Faso.ORCID 0000-0002-8886-5142
Henriette B MihinLaboratory of Microbiology and Microbial Biotechnology, Department of Biochemistry and Microbiology, University Joseph KI-ZERBO, Ouagadougou, 03 BP: 7021, Burkina Faso.
Iliassou MogmengaLaboratory of Biochemistry Biotechnology Food Technology and Nutrition, Department of Biochemistry Microbiology, University Joseph KI-ZERBO, Ouagadougou, 03 BP: 7021, Burkina Faso.
Agbémébia Y AkakpoLaboratory of Microbiology and Microbial Biotechnology, Department of Biochemistry and Microbiology, University Joseph KI-ZERBO, Ouagadougou, 03 BP: 7021, Burkina Faso.
Mamoudou H DickoLaboratory of Biochemistry Biotechnology Food Technology and Nutrition, Department of Biochemistry Microbiology, University Joseph KI-ZERBO, Ouagadougou, 03 BP: 7021, Burkina Faso.ORCID 0000-0003-1212-5946

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bacterial resistance to antibiotics is an important developing threat for human health. Therefore, searching for alternatives through the synergistic combination of essential oils with conventional antibiotics is one of the relevant approaches. This study aims to investigate the mechanism of action of essential oils isolated from local common medicinal plants of Burkina Faso ( Methods: The methodological approach consisted of evaluating the antibacterial activity followed by investigating antibacterial mechanism. Results: The MICs (minimum inhibitory concentration) of Conclusion: It appears from this study that the combinations (essential oil-antibiotic) reduced the MICs of the antibiotics and eradicated antibiotic-resistant bacteria completely. This combination could constitute an excellent means against bacterial resistance to antibiotics.

Indexed as

antibacterial activityantibioticsessential oilsHyptis suaveolensLaggera auritamechanisms

Identifiers

PMID40463480
PMCPMC12132064

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.