SynthesisFrontiers in nutrition2025
Impact of alcohol consumption on hyperuricemia and gout: a systematic review and meta-analysis.
Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Factors associated with hyperuricemia in overweight or obese adults of Shenzhen, China.Scientific reports · 2026Article
- Prevalence of Asymptomatic Hyperuricemia and Associated Factors in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study in Southern Vietnam.Diagnostics (Basel, Switzerland) · 2026Article
- Frequency of erosive arthritis and associated factors in gout patients: a single-center radiological study.Irish journal of medical science · 2026Article
- Preparation and Identification of Corn-Derived Bioactive Peptides with Triple Efficacy of ADH-Activating, XOD-Inhibiting and Antioxidant Activity.Foods (Basel, Switzerland) · 2026Article
- Synergistic effects of ABCG2 Q141K variant in combination with alcohol consumption and male sex on gout risk in a rare-event Taiwanese cohort.Scientific reports · 2026Article
- Development and internal validation of machine learning models for gouty arthritis classification using routine clinical variables: a retrospective study.Frontiers in medicine · 2026Article
- Observational
- Advances in Understanding the Mechanisms of Treatment for Gouty Arthritis: A Comprehensive Review.Physiological research · 2025Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: With the rapid development of socio-economic conditions, the prevalence of hyperuricemia and gout has steadily increased, significantly impacting individuals' quality of life. Among various dietary factors, alcohol consumption plays a crucial role in the onset and progression of these conditions. Despite its importance, systematic evaluations of the impact of alcohol consumption on hyperuricemia and gout remain limited. Therefore, this study conducts a meta-analysis to explore these effects, with a focus on the moderating roles of drinking frequency, gender, and other relevant factors. Methods: A comprehensive literature search was performed using PubMed, Embase, Cochrane, and Web of Science databases up to November 2024. Studies assessing the relationship between alcohol consumption and hyperuricemia or gout were rigorously screened and subjected to quality evaluation. Data extraction and statistical analyses were conducted using STATA 16.0 software. A dose-response analysis was performed to assess the relationship between drinking frequency and disease risk. Regression analysis explored the potential effects of gender, age, country, study type, type of alcohol, and diagnostic criteria on the outcomes. Results: The meta-analysis revealed that alcohol consumption significantly increases the risk of hyperuricemia and gout (OR = 1.69, 95% CI: 1.47-1.94; Z = 7.494, Conclusion: The findings from this meta-analysis confirm that alcohol consumption significantly elevates the risk of hyperuricemia and gout, with higher drinking frequency linked to increased risk. Additionally, male drinkers showed a substantially higher risk compared to female drinkers. These results provide strong evidence supporting the development of public health policies aimed at preventing and controlling hyperuricemia and gout, while offering a foundation for future in-depth research. Systematic review registration: This study has been registered in the International Prospective Register of Systematic Reviews (PROSPERO). The registration details are as follows: CRD42024361042 (https://www.crd.york.ac.uk/PROSPERO/).
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