ArticleFrontiers in nutrition2025
Association of weight-adjusted waist index with preserved ratio impaired spirometry and all-cause mortality.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Dose-response analysis between weight-adjusted waist index and all-cause and cardiovascular mortality: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- The Inflammation-Metabolism Axis in Preserved Ratio Impaired Spirometry: Pathogenic Mechanisms and Translational Implications.Journal of inflammation research · 2026Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Preserved ratio impaired spirometry (PRISm) is considered an early indicator of chronic obstructive pulmonary disease (COPD). This study aimed to investigate the association between weight-adjusted waist index (WWI) and PRISm, and the impact of WWI on all-cause mortality in U.S. adults with and without PRISm. Methods: This combined cross-sectional and cohort study analyzed data from 9,841 participants in the 2007-2012 National Health and Nutrition Examination Survey (NHANES). Weighted logistic regression assessed the association between WWI and PRISm. Kaplan-Meier survival curves and weighted Cox regression evaluated the effect of WWI on all-cause mortality. Restricted cubic spline (RCS) analysis explored both linear and nonlinear relationships between WWI and outcomes. Results: After covariate adjustment, each unit increase in WWI was associated with a 45% reduced risk of PRISm (ORs = 0.55; 95% CIs: 0.47-0.65). RCS analysis revealed a nonlinear WWI-PRISm relationship ( Conclusion: Lower WWI levels were linked to an elevated PRISm risk, highlighting central obesity's role in respiratory health. Maintaining an optimal WWI may mitigate mortality risk in adults with PRISm, emphasizing the need for targeted weight management.
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Registered trials
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