ArticleFrontiers in nutrition2025
Comparative effects of oral nutritional supplementation vs. nutritional education on appetite and weight in older adults with anorexia of aging: a 12-week non-randomized controlled trial.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: With global aging, diet education and oral nutritional supplements (ONS) are recognized for improving nutrition and appetite in older adults, yet evidence on anorexia of aging (AA) mechanisms and interventions remains limited in China. This study aimed to evaluate diet education and ONS efficacy for AA in Chinese community-dwelling older adults. Methods: In an open-label, non-randomized controlled trial, 64 eligible participants were allocated to an ONS group (supplementation) or a diet education group. The Simplified Nutritional Appetite Questionnaire (SNAQ) assessed AA, with follow-ups at weeks 2, 4, 8, and 12. Primary outcomes were SNAQ improvements; secondary outcomes included weight, grip strength, nutritional status (BMI, MNA-SF), cognition (MMSE), mobility (SPPB), mental health (GDS15), and quality of life (EQ-5D). Results: Younger, non-solo-living, and malnourished participants preferred ONS intervention ( Conclusion: Both ONS and diet education alleviated AA over 12 weeks, but ONS demonstrated earlier efficacy (significant SNAQ improvement by week 2). However, ONS did not enhance weight, physical function, or cognitive outcomes. Trial registration: Approved by Peking Union Medical College Hospital Ethics Committee (I-23PJ661), registered at Chinese Clinical Trial Registry (MR-11-23-023104).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.