Evidence map›Paper›PMID 40463417›Full record

ReviewTransplant international : official journal of the European Society for Organ Transplantation2025

Belatacept in Kidney Transplantation: Reflecting on the Past, Shaping the Future.

Johan Noble, Juliette Leon, Arnaud Del Bello, Dany Anglicheau, Gilles Blancho, Simon Ville, Lionel Couzi, Philippe Grimbert, Yannick Le Meur, Bruno Moulin and 5 more

Abstract readReview
In one paragraph

Review in Transplant international : official journal of the European Society for Organ Transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Reversing pregnancy-induced B cell sensitization to facilitate the induction of transplant tolerance in postpartum recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
    Article
  2. Review
  3. Article
  4. Abatacept as maintenance therapy in kidney transplantation: a retrospective comparative study.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Johan NobleNephrology, Hemodialysis, Apheresis and Transplantation, Centre Hospitalier Universitaire (CHU) Grenoble-Alpes, La Tronche, France.
Juliette LeonService des Maladies du Rein et du Métabolisme, Transplantation et Immunologie Clinique, Hôpital Necker, Assistance Publique Hôpitaux de Paris (AP-HP), Paris, France.
Arnaud Del BelloDépartement de Néphrologie et Transplantation d'Organes, Centre Hospitalier Universitaire (CHU) Toulouse, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR 1291, Toulouse Institute for Infectious and Inflammatory Diseases (INFINITY), Université Paul Sabatier, Toulouse, France.
Dany AnglicheauService des Maladies du Rein et du Métabolisme, Transplantation et Immunologie Clinique, Hôpital Necker, Assistance Publique Hôpitaux de Paris (AP-HP), Paris, France.
Gilles BlanchoService de Néphrologie - Immunologie Clinique, Centre Hospitalier Universitaire (CHU) Nantes, Nantes Université, Nantes, France.
Simon VilleService de Néphrologie - Immunologie Clinique, Centre Hospitalier Universitaire (CHU) Nantes, Nantes Université, Nantes, France.
Lionel CouziDepartment of Nephrology, Transplantation, Dialysis and Apheresis, Bordeaux University Hospital, Bordeaux, France.
Philippe GrimbertAssistance Publique Hôpitaux de Paris (AP-HP), Service de Néphrologie et de Transplantation Rénale, Fédération Hospitalo-Universitaire, Innovative Therapy for Immune Disorders, Centre Hospitalier Universitaire (CHU) Henri Mondor, Créteil, France.
Yannick Le MeurDepartment of Nephrology, University Hospital La Cavale Blanche, Université de Bretagne Occidentale, Brest, France.
Bruno MoulinService de Néphrologie-Dialyse-Transplantation, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Nassim KamarDépartement de Néphrologie et Transplantation d'Organes, Centre Hospitalier Universitaire (CHU) Toulouse, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR 1291, Toulouse Institute for Infectious and Inflammatory Diseases (INFINITY), Université Paul Sabatier, Toulouse, France.
Lionel RostaingNephrology, Hemodialysis, Apheresis and Transplantation, Centre Hospitalier Universitaire (CHU) Grenoble-Alpes, La Tronche, France.
Florence Herr *Service de Néphrologie, Transplantation, Hôpital Creteil, Assistance Publique Hôpitaux de Paris (AP-HP), France UMR1186, Institut Gustave Roussy, Université Paris-Saclay, Villejuif, France.
Antoine Durrbach *Service de Néphrologie, Transplantation, Hôpital Creteil, Assistance Publique Hôpitaux de Paris (AP-HP), France UMR1186, Institut Gustave Roussy, Université Paris-Saclay, Villejuif, France.
Dominique Bertrand *Department of Nephrology, Transplantation and Hemodialysis, Rouen University Hospital, Rouen, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcineurin inhibitors (CNIs) are a cornerstone of post-transplant immunosuppressive regimens. However, their use is associated with adverse effects, most notably chronic nephrotoxicity, which remains a leading cause of long-term allograft dysfunction. Belatacept, a selective costimulation blocker, offers a promising alternative to CNIs by aiming to reduce nephrotoxicity while maintaining efficacy in preventing acute rejection. While its use in

Indexed as

AbataceptImmunosuppressive AgentsKidney TransplantationCalcineurin InhibitorsGraft RejectionGraft SurvivalHumansAbataceptCalcineurin InhibitorsImmunosuppressive Agentsbelataceptdonor-specific antibodieseGFRkidney transplantationopportunistic infections

Identifiers

PMID40463417
PMCPMC12129774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.