Evidence map›Paper›PMID 40463389›Full record

ArticleFrontiers in immunology2025

Distribution and potential involvement of PTEN in the innate immune response during viral infections in Cherry Valley ducks.

Wende Chen, Shaojie Han, Rong Li, Shuo Li, Zhi Cao, Qing Pan, Gen Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wende Chen *College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, Shandong, China.
Shaojie Han *Laboratory of Virology, Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Rong LiCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao, Shandong, China.
Shuo LiCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao, Shandong, China.
Zhi CaoCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao, Shandong, China.
Qing PanCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao, Shandong, China.
Gen LiCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Phosphatase and tensin homolog (PTEN) is a well-established tumor suppressor gene that antagonizes the PI3K/AKT signaling pathway and plays a critical role in regulating both innate and adaptive immune responses. However, its function in avian species, particularly in ducks, remains largely unexplored. Methods: In this study, the full-length cDNA of duck PTEN ( Results: Sequence analysis demonstrated that Discussion: This study is the first to characterize the molecular cloning, tissue-specific expression, and virus-induced regulation of

Indexed as

Avian ProteinsDucksImmunity, InnatePoultry DiseasesPTEN PhosphohydrolaseAnimalsFlavivirusPhylogenyReoviridaeAvian ProteinsPTEN PhosphohydrolaseCherry Valley duckcloninginnate immunityPTENviral infection

Identifiers

PMID40463389
PMCPMC12129976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.